PIPA525921

IL-1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA525921-Each-of-1 In Stock ₹ 47,271.90

PIPA525921 - Each of 1

₹ 47,271.90

In Stock

Quantity

1

Base Price: ₹ 47,271.90

GST (18%): ₹ 8,508.942

Total Price: ₹ 55,780.842

Antigen

IL-1 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il1a

Gene Alias

CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3552

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P01583

Gene Symbols

Il1a

Immunogen

KLH conjugated synthetic peptide between 177-206 amino acids from the central region of human IL1A

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
  • IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta
  • IL1A is located on the q arm on chromosome 2 at position 13
  • IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses
  • IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
  • IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis
  • Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis
  • The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2
  • IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases
  • IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO)
  • High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA525921

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Antigen:
IL-1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il1a

Gene Alias:
CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3552

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P01583

Gene Symbols:
Il1a

Immunogen:
KLH conjugated synthetic peptide between 177-206 amino acids from the central region of human IL1A

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA525922

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Antigen:
Calreticulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALR

Gene Alias:
Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12317, 64202, 811

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P14211, P18418, P27797

Gene Symbols:
CALR

Immunogen:
recombinant protein of human CALR.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA525925

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Antigen:
IGFBP4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16010, 3487

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P22692, P47879

Gene Symbols:
IGFBP4

Immunogen:
KLH conjugated synthetic peptide between 96-124 amino acids from the central region of human IGFBP4

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA525940

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Antigen:
Nkx2.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKX2-1

Gene Alias:
AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7080

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P43699

Gene Symbols:
NKX2-1

Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NKX2-1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG