PIPA526689

TLR4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA526689-Each-of-1 In Stock ₹ 44,790.66

PIPA526689 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

TLR4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLR4

Gene Alias

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7099

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O00206

Gene Symbols

TLR4

Immunogen

KLH conjugated synthetic peptide between 669-698 amino acids from the central region of human TLR4

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, hamster and porcine based on sequence homology
  • TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
  • Mammalian cells respond to LPS by activating TLR4
  • TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
  • TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
  • Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
  • TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
  • Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
  • Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA526689

--


Antigen:
TLR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7099

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O00206

Gene Symbols:
TLR4

Immunogen:
KLH conjugated synthetic peptide between 669-698 amino acids from the central region of human TLR4

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA526692

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Antigen:
AFF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AFF4

Gene Alias:
AF4/FMR2 family member 4; AF4/FMR2 family, member 4; AF5Q31; Aff4; Alf4; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; CHOPS; HSPC092; Laf4l; LOW QUALITY PROTEIN: AF4/FMR2 family member 4; major CDK9 elongation factor-associated protein; MCEF; Protein AF-5q31; RA_m002_jsmFBA6Br

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27125

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9UHB7

Gene Symbols:
AFF4

Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AF5q31

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA526699

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Antigen:
Cytokeratin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT1

Gene Alias:
67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; epithelial keratin 1; Epithelial keratin-1; EPPK; Hair alpha protein; K1; Kb1; KER1; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 86; keratin complex 2, basic, gene 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1; krt1 {ECO:0000250; KRT1A; Krt-2.1; Krt2-1; Krt86; KRTA; NEPPK; type II keratin Kb1; type-II keratin Kb1; UniProtKB:P04264}

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
3848

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P04264

Gene Symbols:
KRT1

Immunogen:
KLH conjugated synthetic peptide between 415-443 amino acids from the central region of human KRT1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA526701

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Antigen:
Oxytocin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OXT

Gene Alias:
neurophysin 1; neurophysin I; Ocytocin; Ot; OT-NPI; oxcytocin; OXT; OXT-NPI; Oxy; Oxytocin; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; oxytocin/neurophysin (Oxt) gene, complete gene, complete cds; oxytocin/neurophysin 1 prepropeptide; oxytocin/neurophysin I prepropeptide; oxytocin-neurophysin 1; oxytocin-neurophysin I; oxytocin-neurophysin I, preproprotein; prepropeptide for oxytocin and neurophysin; unnamed protein product

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
5020

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P01178

Gene Symbols:
OXT

Immunogen:
KLH conjugated synthetic peptide between 11-40 amino acids from the central region of human NEU1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG