PIPA527134

Cortactin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527134-Each-of-1 In Stock ₹ 50,052.60

PIPA527134 - Each of 1

₹ 50,052.60

In Stock

Quantity

1

Base Price: ₹ 50,052.60

GST (18%): ₹ 9,009.468

Total Price: ₹ 59,062.068

Antigen

Cortactin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cttn

Gene Alias

1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13043, 2017, 60465

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q14247, Q60598, Q66HL2

Gene Symbols

Cttn

Immunogen

Synthetic peptide corresponding to a region within amino acids 1 and 43 of Human Cortactin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, HepG2, NIH-3T3, JC, PC-12, mouse brain, rat brain
  • Predicted reactivity: Rhesus Monkey (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Cortactin (Cttn) is a ubiquitous actin-binding protein that was originally identified as a substrate for Src
  • It contributes to the organization of the actin cytoskeleton and cell shape
  • Cortactin also plays a role in the formation of lamellipodia and cell migration
  • It is accumulated in peripheral, actin-enriched structures of cells suggesting that cortactin facilitates actin network formation
  • Cortactin has four major domains of interest the N-terminal acidic (NTA) and tandem repeats domains and the C-terminal proline-rich and SH3 Domains
  • NTA associates with the Arp2/3 and WASP complex at F-actin branches
  • Cortactin is involved in promoting cell motility and invasion, including a critical role in invadopodia, actin rich-subcellular protrusions associated with degradation of the ECM by cancer cells
  • Cortactin is phosphorylated by src family kinases at Y421, Y466, and Y482 and S405 and S418 that are phosphorylated by Erk family kinases.

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Thermo Scientific

PIPA527134

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Antigen:
Cortactin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cttn

Gene Alias:
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13043, 2017, 60465

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q14247, Q60598, Q66HL2

Gene Symbols:
Cttn

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 43 of Human Cortactin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA527138

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Antigen:
FCGR2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FCGR2B

Gene Alias:
AI528646; CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); fc gamma receptor IIB; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; Fc[g]RII; FCG2; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; FcgammaRIIB; fc-gamma-RIIb; FcgammaRIIB2; FcGR; Fcgr2; Fcgr2a; FCGR2A1; FCGR2B; FcgRII; Fcr-2; Fcr-3; fcRII; fcRII-a; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II beta; igG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; LyM-1; Ly-m20; Lymphocyte antigen 17

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2213

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P31994

Gene Symbols:
FCGR2B

Immunogen:
Synthetic peptide corresponding to a region within amino acids 248 and 310 of Human CD32B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527140

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Antigen:
FGR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGR

Gene Alias:
c-fgr; c-fgr protooncogene; c-src2; c-src-2 proto-oncogene; EC 2.7.10.2; feline Gardner-Rasheed sarcoma viral oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; FGR; FGR protein; FGR proto-oncogene, Src family tyrosine kinase; FLJ43153; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; OTTHUMP00000003603; OTTHUMP00000003604; p55c-fgr; p55-c-fgr protein; p55-Fgr; p58c-Fgr; p58-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; SRC2; Tyrosine-protein kinase Fgr; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2268

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P09769

Gene Symbols:
FGR

Immunogen:
Synthetic peptide corresponding to a region within amino acids 467 and 529 of Human FGR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527141

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Antigen:
FHL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FHL1

Gene Alias:
bA535K18.1; cb1039; fhl; Fhl1; FHL-1; FHL1A; fhl1b; fhla; FLH1A; four and a half LIM domains; four and a half LIM domains 1; four and a half LIM domains 1a; four and a half LIM domains 1b; four and a half LIM domains 1b; four and a half LIM domains protein 1b; four and a half LIM domains a; four and a half LIM domains protein 1; four and a half LIM domains protein 1; four and a half LIM domains protein 1a; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYOT; KYO-T; LIM protein; LIM protein SLIMMER; MGC111107; RAM14-1; RBMX1A; RBMX1B; RBP-associated molecule 14-1; RP11-535K18.1; skeletal muscle LIM-protein 1; SLIM; SLIM1; SLIM-1; SLIMMER; XMPMA; zgc:92025

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14199, 2273

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P97447, Q13642

Gene Symbols:
FHL1

Immunogen:
Synthetic peptide corresponding to a region within amino acids 211 and 262 of Human FHL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG