PIPA527629
APOBEC3C Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527629-Each-of-1 | In Stock | ₹ 44,790.66 |
PIPA527629 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,790.66
GST (18%): ₹ 8,062.319
Total Price: ₹ 52,852.979
Antigen
APOBEC3C
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APOBEC3C
Gene Alias
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27350
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NRW3
Gene Symbols
APOBEC3C
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 190 of Human APOBEC3C
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: NCI-H929
- Predicted reactivity: Rhesus Monkey (84%), Chimpanzee (97%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
- The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
- Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
- Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
- Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
- Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
- This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
Compare Similar Items
Show Difference
Antigen: APOBEC3C
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOBEC3C
Gene Alias: A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27350
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NRW3
Gene Symbols: APOBEC3C
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 190 of Human APOBEC3C
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APOBEC3C
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOBEC3C
Gene Alias:
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27350
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NRW3
Gene Symbols:
APOBEC3C
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 190 of Human APOBEC3C
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: KARS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KARS1
Gene Alias: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3735
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.77 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q15046
Gene Symbols: KARS1
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 215 of Human Lysyl-tRNA synthetase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
KARS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KARS1
Gene Alias:
AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3735
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.77 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q15046
Gene Symbols:
KARS1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 215 of Human Lysyl-tRNA synthetase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MEK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP2K2
Gene Alias: AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5605
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.97 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P36507
Gene Symbols: MAP2K2
Immunogen: Recombinant fragment corresponding to a region within amino acids 188 and 396 of Human MEK2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MEK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP2K2
Gene Alias:
AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5605
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.97 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P36507
Gene Symbols:
MAP2K2
Immunogen:
Recombinant fragment corresponding to a region within amino acids 188 and 396 of Human MEK2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TSFM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSFM
Gene Alias: 2310050B20Rik; 2A3-2; 9430024O13Rik; EFTS; EF-Ts; EF-Ts {ECO:0000255; EFTSMT; EF-TsMt; EF-TsMt {ECO:0000255; elongation factor Ts; elongation factor Ts, mitochondrial; elongation factor Ts, mitochondrial {ECO:0000255; HAMAP-Rule:MF_03135}; mitochondrial elongation factor Ts; translation elongation factor; Ts translation elongation factor, mitochondrial; TSFM; zgc:158429
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10102, 66399
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.88 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P43897, Q9CZR8
Gene Symbols: TSFM
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 196 of Human TSFM
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TSFM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSFM
Gene Alias:
2310050B20Rik; 2A3-2; 9430024O13Rik; EFTS; EF-Ts; EF-Ts {ECO:0000255; EFTSMT; EF-TsMt; EF-TsMt {ECO:0000255; elongation factor Ts; elongation factor Ts, mitochondrial; elongation factor Ts, mitochondrial {ECO:0000255; HAMAP-Rule:MF_03135}; mitochondrial elongation factor Ts; translation elongation factor; Ts translation elongation factor, mitochondrial; TSFM; zgc:158429
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10102, 66399
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.88 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P43897, Q9CZR8
Gene Symbols:
TSFM
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 196 of Human TSFM
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG