PIPA527698

AIF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA527698-Each-of-1 In Stock ₹ 49,496.46

PIPA527698 - Each of 1

₹ 49,496.46

In Stock

Quantity

1

Base Price: ₹ 49,496.46

GST (18%): ₹ 8,909.363

Total Price: ₹ 58,405.823

Antigen

AIF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9131

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.72 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O95831

Gene Symbols

AIFM1

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 170 of Human AIF

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: 293T, A431, HeLa, HepG2, A375
  • Predicted reactivity: Pig (81%), Bovine (85%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

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Thermo Scientific

PIPA527698

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Antigen:
AIF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9131

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.72 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95831

Gene Symbols:
AIFM1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 170 of Human AIF

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527701

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Antigen:
BAG2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAG2

Gene Alias:
2610042A13Rik; BAG cochaperone 2; BAG family molecular chaperone regulator 2; BAG2; BAG-2; BAG-family molecular chaperone regulator-2; BC016230; BCL2 associated athanogene 2; Bcl-2-associated athanogene 2; Bcl2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; RP3-496N17.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9532

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95816

Gene Symbols:
BAG2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 211 of Human BAG2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527702

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Antigen:
CDK13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk13

Gene Alias:
2310015O17Rik; CDC2L; Cdc2l5; CDC2-related protein kinase 5; CDK13; cell division cycle 2-like 5 (cholinesterase-related cell division controller); cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; CHED; Cholinesterase-related cell division controller; cyclin dependent kinase 13; cyclin-dependent kinase 13; hCDK13; Kiaa1791

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8621

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.78 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q14004

Gene Symbols:
Cdk13

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 372 and 586 of Human CDC2L5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA527704

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Antigen:
p19 INK4d

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2D

Gene Alias:
CDK inhibitor p19INK4d; CDK4I; CDKN2D; cell cycle inhibitor, Nur77 associating protein; cyclin dependent kinase inhibitor 2D; cyclin-dependent kinase 4 inhibitor D; cyclin-dependent kinase 4 inhibitor D p19; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; INK4d; MTS1; p16-INK4; p16-INK4a; p19; p19INK4d; p19-INK4D; similar to cyclin-dependent kinase inhibitor 2D

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1032, 494444

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P55273

Gene Symbols:
CDKN2D

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 165 of Human p19 INK4d

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG