PIPA527742

ABCB11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527742-Each-of-1 In Stock ₹ 47,528.58

PIPA527742 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

ABCB11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABCB11

Gene Alias

ABC member 16, MDR/TAP subfamily; ABC16; Abcb11; ATP binding cassette subfamily B member 11; ATP-binding cassette sub-family B member 11; ATP-binding cassette, subfamily B (MDR/TAP), member 11; ATP-binding cassette, sub-family B (MDR/TAP), member 11; ATP-binding cassette, sub-family B, member 11; bile salt export pump; BRIC2; Bsep; Lith1; PFIC2; PFIC-2; PGY4; progressive familial intrahepatic cholestasis 2; sister of P-glycoprotein; sister p-glycoprotein; Spgp

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

8647

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.17 mg/mL

Formulation

1 XPBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

O95342

Gene Symbols

ABCB11

Immunogen

Recombinant fragment corresponding to a region within amino acids 474 and 745 of Human BSEP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: Jurkat
  • Predicted reactivity: Mouse (85%), Rat (87%), Dog (84%), Cat (87%), Rabbit (85%), Bovine (88%), Guinea pig (81%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ABCB11 is involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes
  • It is expressed predominatly, if not exclusively, in the liver, where it is further localized to the canilicular microvilli and to subcanilicular vesicles fo the hepatocytes
  • Structurally, ABCB11 is a multifunctional polypeptide with two homologus halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain
  • Defects in ABCB11 are the cause of progressive familial intrahepatic cholestasis 2 (PFIC2)
  • PFIC2 is an inherited liver disease of childhood which is characterized by cholestasis and normal serum gamma-glutamyltransferase activity
  • Defects in ABCB11 are also found in cases of chronic intrahepatic cholestasis without obvious familial history of chronic liver disease.

Compare Similar Items

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Img

Thermo Scientific

PIPA527742

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Antigen:
ABCB11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCB11

Gene Alias:
ABC member 16, MDR/TAP subfamily; ABC16; Abcb11; ATP binding cassette subfamily B member 11; ATP-binding cassette sub-family B member 11; ATP-binding cassette, subfamily B (MDR/TAP), member 11; ATP-binding cassette, sub-family B (MDR/TAP), member 11; ATP-binding cassette, sub-family B, member 11; bile salt export pump; BRIC2; Bsep; Lith1; PFIC2; PFIC-2; PGY4; progressive familial intrahepatic cholestasis 2; sister of P-glycoprotein; sister p-glycoprotein; Spgp

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8647

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.17 mg/mL

Formulation:
1 XPBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O95342

Gene Symbols:
ABCB11

Immunogen:
Recombinant fragment corresponding to a region within amino acids 474 and 745 of Human BSEP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527743

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Antigen:
MAGI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Magi1

Gene Alias:
AIP3; AIP-3; Atrophin-1-interacting protein 3; BAI1-associated protein 1; Baiap1; BAP1; BAP-1; Gukmi1; MAGI1; Magi-1; MAGI1c; Magi1d; membrane associated guanylate kinase, WW and PDZ domain containing 1; membrane-associated guanylate kinase inverted 1; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; mKIAA4129; TNRC19; Trinucleotide repeat-containing gene 19 protein; WW domain-containing protein 3; WWP3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14924, 9223

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q6RHR9, Q96QZ7

Gene Symbols:
Magi1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1024 and 1236 of Human MAGI1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527744

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Antigen:
UBA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBA2

Gene Alias:
AA986091; Anthracycline-associated resistance ARX; Arx; EGK_10449; FLJ13058; HRIHFB2115; SAE2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA1; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin like modifier activating enzyme 2; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; ubiquitin-like modifier-activating enzyme 2; Ubl1a2; Uble1b

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10054

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9UBT2

Gene Symbols:
UBA2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 4 and 216 of Human UBA2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527747

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Antigen:
DYRK1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DYRK1B

Gene Alias:
AOMS3; dual specificity tyrosine phosphorylation regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; DYRKB; Minibrain-related kinase; Mirk; Mirk protein kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13549, 9149

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9Y463, Q9Z188

Gene Symbols:
DYRK1B

Immunogen:
Recombinant fragment corresponding to a region within amino acids 11 and 230 of Human DYRK1B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG