PIPA527765

TPL2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA527765-Each-of-1 In Stock ₹ 44,705.10

PIPA527765 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TPL2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K8

Gene Alias

augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1326, 26410

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.98 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P41279, Q07174

Gene Symbols

MAP3K8

Immunogen

Recombinant fragment corresponding to a region within amino acids 223 and 467 of Human MAP3K8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji
  • Predicted reactivity: Mouse (94%), Rat (95%), Bovine (97%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
  • Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
  • MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
  • The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
  • MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
  • This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
  • The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
  • The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.

Compare Similar Items

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Img

Thermo Scientific

PIPA527765

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Antigen:
TPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1326, 26410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.98 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P41279, Q07174

Gene Symbols:
MAP3K8

Immunogen:
Recombinant fragment corresponding to a region within amino acids 223 and 467 of Human MAP3K8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527768

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Antigen:
WTAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WTAP

Gene Alias:
2810408K05Rik; 9430038B09Rik; Female-lethal(2)D homolog; hFL(2)D; KIAA0105; Mum2; PNAS-132; pre-mRNA-splicing regulator WTAP; putative pre-mRNA splicing regulator female-lethal(2D); RGD1563824; Wilms tumor 1 associated protein; wilms tumor 1-associating protein; Wilms' tumour 1-associating protein; Wilms tumour 1-associating protein; WT1-associated protein; WTAP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9589

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q15007

Gene Symbols:
WTAP

Immunogen:
Recombinant fragment corresponding to a region within amino acids 180 and 396 of Human WTAP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527769

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Antigen:
CYP4F2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYP4F2

Gene Alias:
20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; Arachidonic acid omega-hydroxylase; CPF2; CYP4F2; CYPIVF2; cytochrome P450 4F2; cytochrome P450 family 4 subfamily F member 2; cytochrome P450, family 4, subfamily F, polypeptide 2; cytochrome P450, subfamily IVF, polypeptide 2; cytochrome P450-LTB-omega; Docosahexaenoic acid omega-hydroxylase; docosahexaenoic acid omega-hydroxylase CYP4F3; phylloquinone omega-hydroxylase CYP4F2; leukotriene-B(4) 20-monooxygenase 1; Leukotriene-B(4) omega-hydroxylase 1; phylloquinone omega-hydroxylase CYP4F2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100113470, 8529

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P78329

Gene Symbols:
CYP4F2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 162 and 400 of Human Cytochrome P450 4F2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527770

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Antigen:
PPAT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppat

Gene Alias:
5730454C12Rik; AA408689; AA675351; AI507113; Amidophosphoribosyltransferase; amidophosphoribosyltransferase proprotein; amidophosphoribosyltransferase-like protein; ATASE; C79945; EC 2.4.2.14; EGK_15868; glutamine phosphoribosylpyrophosphatate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT; phosphoribosyl pyrophosphate amidotransferase; PPAT; PRAT

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5471

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q06203

Gene Symbols:
Ppat

Immunogen:
Recombinant fragment corresponding to a region within amino acids 283 and 517 of Human PPAT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG