PIPA527827

CDK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA527827-Each-of-1 In Stock ₹ 50,223.72

PIPA527827 - Each of 1

₹ 50,223.72

In Stock

Quantity

1

Base Price: ₹ 50,223.72

GST (18%): ₹ 9,040.27

Total Price: ₹ 59,263.99

Antigen

CDK4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1019, 12567, 510618, 94201

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.82 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P11802, P30285, P35426, Q32KY4

Gene Symbols

Cdk4

Immunogen

Recombinant fragment corresponding to a region within amino acids 148 and 303 of Human CDK4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, PC-12
  • Predicted reactivity: Mouse (95%), Rat (94%), Pig (98%), Sheep (96%), Rhesus Monkey (100%), Bovine (96%)
  • CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
  • CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
  • CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
  • CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
  • CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
  • SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
  • Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA527827

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Antigen:
CDK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk4

Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1019, 12567, 510618, 94201

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.82 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P11802, P30285, P35426, Q32KY4

Gene Symbols:
Cdk4

Immunogen:
Recombinant fragment corresponding to a region within amino acids 148 and 303 of Human CDK4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA527828

--


Antigen:
Collagen III

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Col3a1

Gene Alias:
alpha1 (III) collagen; alpha-1 collagen type III; alpha-1 type III collagen; alpha-1 type-3 collagen; AW550625; COL 3; COL3; COL3 alpha 1; COL3A1; Col3a-1; collagen; Collagen 3; collagen alpha 1 type III; collagen alpha-1(III) chain; collagen type III alpha 1 chain; collagen, fetal; collagen, type III, alpha 1; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); collagen, type III, alpha 1 chain, fibril forming; Collagen3; EDS4A; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; mKIAA4231; MMS10-W; Ms10w; PIIINP; pro alpha 1 type III collagen; procollagen, type III, alpha 1; unknown

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1281

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.42 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P02461

Gene Symbols:
Col3a1

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1180 and 1444 of Human COL3A1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527830

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Antigen:
CRYGC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRYGC

Gene Alias:
CCL; Cryg; Cryg3; Cryg-5; Crygc; crystallin gamma C; crystallin, gamma C; crystallin, gamma polypeptide 3; CTRCT2; Gammab-cry; Gamma-C-crystallin; gammaC-crystallin; gamma-crystallin 2-1; Gamma-crystallin 3; gamma-crystallin C; Gamma-crystallin IIIA; Len

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12966, 1420

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P07315, Q61597

Gene Symbols:
CRYGC

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 174 of Human gamma C Crystallin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA527833

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Antigen:
MCAK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF2C

Gene Alias:
4930402F02Rik; CT139; ESTM5; hypothetical protein; KIF2C; kinesin family member 2C; kinesin-like 6; kinesin-like protein 6; Kinesin-like protein KIF2C; kinesin-related protein 2; KNSL6; KRP2; MCAK; Mitotic centromere-associated kinesin; QtsA-16015; RP11-269F19.1; testis tissue sperm-binding protein Li 68n; X83316

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11004

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99661

Gene Symbols:
KIF2C

Immunogen:
Recombinant fragment corresponding to a region within amino acids 9 and 287 of Human MCAK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG