PIPA527914

FPGS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527914-Each-of-1 In Stock ₹ 47,015.22

PIPA527914 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

FPGS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FPGS

Gene Alias

AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase; folylpolyglutamate synthase, mitochondrial; folylpolyglutamyl synthetase; FPGS; Tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2356

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q05932

Gene Symbols

FPGS

Immunogen

Recombinant fragment corresponding to a region within amino acids 222 and 488 of Human Folylpolyglutamate synthase

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: Folylpolyglutamate synthase tansfected 293T cell
  • Predicted reactivity: Bovine (81%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Folylpoly-gamma-glutamate synthetase (FPGS) catalyzes the addition of several equivalents of glutamic acid to the gamma-carboxyl group in the side chain of folate cofactors and analogs
  • Folylpoly-gamma-glutamate synthetase has three functions in folate homeostasis in mammals: polyglutamation prevents efflux of folate cofactors from the cell, it increases the binding of folate cofactors to some of the enzymes of folate interconversion and biosynthesis, and it appears to allow the accumulation of folates in the mitochondria that are required for glycine synthesis
  • Folylpoly-gamma-glutamate synthetase is widely expressed in human tumors and is tightly linked either to proliferation or to a lack of differentiation
  • The cytotoxicity of both thymidylate synthase and purine inhibitors requires continued inhibition of target for greater than one generation time, so that the integrative function of FPGS adds considerably to the efficiency of folate antimetabolites.

Compare Similar Items

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Img

Thermo Scientific

PIPA527914

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Antigen:
FPGS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FPGS

Gene Alias:
AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase; folylpolyglutamate synthase, mitochondrial; folylpolyglutamyl synthetase; FPGS; Tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2356

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q05932

Gene Symbols:
FPGS

Immunogen:
Recombinant fragment corresponding to a region within amino acids 222 and 488 of Human Folylpolyglutamate synthase

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527915

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Antigen:
Monoacylglycerol Lipase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MGLL

Gene Alias:
AA589436; HUK5; HU-K5; lysophospholipase homolog; Lysophospholipase-like; MAGL; Mgl; Mgl2; MGLL; Monoacylglycerol lipase; monoglyceride lipase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11343, 23945, 29254

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O35678, Q8R431, Q99685

Gene Symbols:
MGLL

Immunogen:
Recombinant fragment corresponding to a region within amino acids 36 and 303 of Human Monoglyceride lipase

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527916

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Antigen:
FMO3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fmo3

Gene Alias:
AW111792; Dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline oxidase 3; dJ127D3.1; flavin containing dimethylaniline monoxygenase 3; flavin containing monooxygenase 3; flavin-containing monooxygenase 3; flavin-containing monooxygenase FMO3; FM03; FMO 1D1; FMO 3; FMO form 2; FMO II; FMO3; FMOII; hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; TMAU; Trimethylamine monooxygenase; Unknown (protein for MGC:128044)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14262, 2328

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P31513, P97501

Gene Symbols:
Fmo3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 122 and 394 of Human FMO3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA527917

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Antigen:
PSKH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pskh1

Gene Alias:
AW539964; b2b1230Clo; E130013P03Rik; Mutant line 1230; protein serine kinase H1; PSKH1; PSK-H1; Serine/threonine-protein kinase H1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5681

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P11801

Gene Symbols:
Pskh1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 258 of Human PSKH1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG