PIPA527928

CD22 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527928-Each-of-1 In Stock ₹ 44,705.10

PIPA527928 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CD22

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD22

Gene Alias

A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

933

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P20273

Gene Symbols

CD22

Immunogen

Recombinant fragment corresponding to a region within amino acids 193 and 710 of Human CD22

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: Raji
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA527928

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Antigen:
CD22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Recombinant fragment corresponding to a region within amino acids 193 and 710 of Human CD22

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527932

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Antigen:
ELF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Elf4

Gene Alias:
AV314029; BC042423; E74 like ETS transcription factor 4; E74-like factor 4; E74-like factor 4 (ets domain transcription factor); E74-like factor 4; myeloid elf-1-like factor; myeloid elf-1 like factor; ELF4; ELFR; ENSMUSG00000053512; ETS-related transcription factor Elf-4; Gm9907; MEF; myeloid elf-1 like factor; myeloid Elf-1-like factor; RGD1560743

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2000

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99607

Gene Symbols:
Elf4

Immunogen:
Recombinant fragment corresponding to a region within amino acids 60 and 323 of Human ELF4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA527934

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Antigen:
DNAJB12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJB12

Gene Alias:
DJ10; DKFZp586B2023; DnaJ (Hsp40) homolog, subfamily B, member 12; DnaJ heat shock protein family (Hsp40) member B12; DnaJ homolog 10; dnaJ homolog subfamily B member 12; DnaJ subfamily B member 12-like protein; Dnajb12; LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12; mDj10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54788

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.89 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9NXW2

Gene Symbols:
DNAJB12

Immunogen:
Recombinant fragment corresponding to a region within amino acids 82 and 353 of Human DNAJB12

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA527937

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Antigen:
Nectin 3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NECTIN3

Gene Alias:
2610301B19Rik; 3000002N23Rik; 4921513D19Rik; AA407785; AU016832; AW538082; CD113; CDW113; DKFZP566B0846; FLJ90624; nectin 3; nectin cell adhesion molecule 3; Nectin3; Nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3; PVRL3; PVRR3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25945, 288124, 58998

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9JLB9, Q9NQS3

Gene Symbols:
NECTIN3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 115 and 353 of Human Nectin 3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG