PIPA528069

Tankyrase 2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA528069-Each-of-1 In Stock ₹ 47,528.58

PIPA528069 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Tankyrase 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNKS2

Gene Alias

5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80351

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.25 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9H2K2

Gene Symbols

TNKS2

Immunogen

Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human Tankyrase 2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2
  • Predicted reactivity: Mouse (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:11739745, PubMed:11802774, PubMed:19759537, PubMed:21478859, PubMed:23622245, PubMed:25043379)
  • Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation (PubMed:19759537, PubMed:21478859)
  • Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination (PubMed:21478859)
  • Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length (PubMed:11739745)
  • Stimulates 26S proteasome activity (PubMed:23622245)
  • [UniProt]

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Img

Thermo Scientific

PIPA528069

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Antigen:
Tankyrase 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNKS2

Gene Alias:
5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.25 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9H2K2

Gene Symbols:
TNKS2

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human Tankyrase 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA528070

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Antigen:
PIK3CG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIK3CG

Gene Alias:
1-phosphatidylinositol 3-kinase; 5830428L06Rik; EGK_14026; p110gamma; p110-gamma; p120-PI3K; phosphatidylinositol 3 kinase gamma, p110 gamma; phosphatidylinositol 3-kinase catalytic 110-kD gamma; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; phosphoinositide-3-kinase gamma catalytic subunit; phosphoinositide-3-kinase, catalytic, gamma polypeptide; PI3CG; PI3K; pi3kcg; Pi3kg1; PI3Kgamma; PI3K-gamma; PI3-kinase subunit gamma; PIK3; Pik3cg; ptdIns-3-kinase subunit gamma; ptdIns-3-kinase subunit p110-gamma; Serine/threonine protein kinase PIK3CG

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298947, 30955, 5294

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P48736, Q9JHG7

Gene Symbols:
PIK3CG

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1041 and 1102 of Human PI3 kinase p110 gamma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA528072

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Antigen:
USP28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP28

Gene Alias:
9830148O20Rik; AU022237; Deubiquitinating enzyme 28; Kiaa1515; mKIAA1515; ubiquitin carboxyl-terminal hydrolase 28; ubiquitin carboxyl-terminal hydrolase 28 variant 1; ubiquitin specific peptidase 28; ubiquitin specific protease 28; ubiquitin thioesterase 28; ubiquitin thiolesterase 28; ubiquitin-specific-processing protease 28; Usp28

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57646

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96RU2

Gene Symbols:
USP28

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1015 and 1077 of Human USP28

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA528073

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Antigen:
EPM2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPM2A

Gene Alias:
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha; epilepsy, progressive myoclonus type 2, Lafora disease (laforin); epilepsy, progressive myoclonus type 2A; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); EPM2; EPM2A; EPM2A glucan phosphatase, laforin; EPM2A, laforin glucan phosphatase; glucan phosphatase; Glycogen phosphatase; Lafora PTPase; laforin; LAFPTPase; MELF; RP1-28C20.2; Tg(TcraK,TcrbK)TG-BFlv; TG-B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7957

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
B3EWF7

Gene Symbols:
EPM2A

Immunogen:
Synthetic peptide corresponding to a region within amino acids 270 and 331 of Human Laforin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG