PIPA528079
CHFR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528079-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA528079 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CHFR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Chfr
Gene Alias
5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55743
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96EP1
Gene Symbols
Chfr
Immunogen
Synthetic peptide corresponding to a region within amino acids 602 and 664 of Human CHFR
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: A431, H1299, NT2D1, A549, HCT116
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons
- Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus
- Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome
- Promotes the ubiquitination and subsequent degradation of AURKA and PLK1
- Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation
- May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer
- Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.
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Antigen: CHFR
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Chfr
Gene Alias: 5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55743
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q96EP1
Gene Symbols: Chfr
Immunogen: Synthetic peptide corresponding to a region within amino acids 602 and 664 of Human CHFR
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CHFR
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Chfr
Gene Alias:
5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55743
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q96EP1
Gene Symbols:
Chfr
Immunogen:
Synthetic peptide corresponding to a region within amino acids 602 and 664 of Human CHFR
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RNF25
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNF25
Gene Alias: 0610009H16Rik; AO7; E3 ubiquitin-protein ligase RNF25; ring finger protein 25; RING finger protein AO7; RING-type E3 ubiquitin transferase RNF25; RNF25
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64320
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q96BH1
Gene Symbols: RNF25
Immunogen: Synthetic peptide corresponding to a region within amino acids 377 and 459 of Human RNF25
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RNF25
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNF25
Gene Alias:
0610009H16Rik; AO7; E3 ubiquitin-protein ligase RNF25; ring finger protein 25; RING finger protein AO7; RING-type E3 ubiquitin transferase RNF25; RNF25
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64320
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q96BH1
Gene Symbols:
RNF25
Immunogen:
Synthetic peptide corresponding to a region within amino acids 377 and 459 of Human RNF25
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FZD8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fzd8
Gene Alias: frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8325
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9H461
Gene Symbols: Fzd8
Immunogen: Synthetic peptide corresponding to a region within amino acids 634 and 694 of Frizzled 8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FZD8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fzd8
Gene Alias:
frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8325
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9H461
Gene Symbols:
Fzd8
Immunogen:
Synthetic peptide corresponding to a region within amino acids 634 and 694 of Frizzled 8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NOTCH3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Notch3
Gene Alias: AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4854
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 5.26 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9UM47
Gene Symbols: Notch3
Immunogen: Synthetic peptide corresponding to a region within amino acids 2256 and 2321 of Human Notch 3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NOTCH3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Notch3
Gene Alias:
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4854
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
5.26 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9UM47
Gene Symbols:
Notch3
Immunogen:
Synthetic peptide corresponding to a region within amino acids 2256 and 2321 of Human Notch 3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG