PIPA528451
FSTL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528451-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA528451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
FSTL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Fstl1
Gene Alias
AI316791; AW107808; FLJ50214; FLJ52277; follistatin like 1; follistatin-like 1; follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; Fstl; FSTL1; MIR198; OCC1; OCC-1; TGF-beta-inducible protein TSC-36; tsc36; TSC-36
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11167
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.76 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q12841
Gene Symbols
Fstl1
Immunogen
Synthetic peptide corresponding to a region within amino acids 246 and 308 of Human FSTL1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa
- Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Follistatin-like protein 1 (FSTL1) is a widely-expressed, extracellular glycoprotein that is homologously grouped into the osteonectin (BM-40/SPARC) family of secreted proteins based on its possession of both a follistatin-like and extracellular calcium-binding domain
- Initially identified as a TGF-beta-inducible protein in a cloned mouse osteoblast cell line, FSTL1 has since been implicated in an array of cell-type-specific functions, such as the regulation of proliferation, differentiation, apoptosis and migration, as well as a number of biological processes, including embryonic development, inflammatory response, angiogenesis, tumorigenesis, and immune disease pathogenesis
- Highly conserved across mammalian species and widely expressed in human tissues, FSTL1 can be upregulated through signaling mediators of the innate immune system,such as TLR4 agonists and the arthritogenic cytokine IL-1beta via NFkappaB pathways, to stimulate the expression and secretion of pro-inflammatory cytokines, including TNF-alpha, IL-1beta, IL-6 and IL-8
- While cells of mesenchymal lineage are capable of FSTL1 production, FSTL1 expression is notably absent from cells of hematopoietic lineage under normal physiological conditions
- Macrophages and monocytes are, however, capable of taking up FSTL1 at sites of inflammation where FSTL1 stimulation can cause the expression of caspase-1 and its resultant enzymatic cleavage of active IL-1beta from pro-IL-1beta
- Whereas the overexpression of FSTL1 has been noted as a substantial contributor to the progression of immune diseases like rheumatoid arthritis (RA) and osteoarthritis (OA), diminished FSTL1 serum levels have been identified as playing a significant part in both ovarian and endometrial carcinogenesis, where it directly affects cell proliferation, migration and invasion.
Compare Similar Items
Show Difference
Antigen: FSTL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fstl1
Gene Alias: AI316791; AW107808; FLJ50214; FLJ52277; follistatin like 1; follistatin-like 1; follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; Fstl; FSTL1; MIR198; OCC1; OCC-1; TGF-beta-inducible protein TSC-36; tsc36; TSC-36
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11167
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.76 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q12841
Gene Symbols: Fstl1
Immunogen: Synthetic peptide corresponding to a region within amino acids 246 and 308 of Human FSTL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FSTL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fstl1
Gene Alias:
AI316791; AW107808; FLJ50214; FLJ52277; follistatin like 1; follistatin-like 1; follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; Fstl; FSTL1; MIR198; OCC1; OCC-1; TGF-beta-inducible protein TSC-36; tsc36; TSC-36
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11167
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.76 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q12841
Gene Symbols:
Fstl1
Immunogen:
Synthetic peptide corresponding to a region within amino acids 246 and 308 of Human FSTL1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NUP50
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUP50
Gene Alias: 1700030K07Rik; 50 kDa nucleoporin; AI413123; CTA-268H5.7; DKFZP564A043; MGC39961; Npap60; NPAP60L; nuclear pore associated protein; nuclear pore associated protein 60 kDa; nuclear pore complex protein Nup50; nuclear pore complex protein Nup50; LOW QUALITY PROTEIN: nuclear pore complex protein Nup50; nuclear pore complex protein nup50-like protein; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50; nucleoporin 50 kDa; Nucleoporin 50 kDa-like protein; nucleoporin 50kD; nucleoporin 50kDa; nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; Nup50; NUP50 protein; OTTHUMP00000199530; PRO1146; Rtp60; Unknown (protein for MGC:134469)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10762, 18141
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.79 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9JIH2, Q9UKX7
Gene Symbols: NUP50
Immunogen: Synthetic peptide corresponding to a region within amino acids 407 and 468 of Human NUP50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NUP50
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUP50
Gene Alias:
1700030K07Rik; 50 kDa nucleoporin; AI413123; CTA-268H5.7; DKFZP564A043; MGC39961; Npap60; NPAP60L; nuclear pore associated protein; nuclear pore associated protein 60 kDa; nuclear pore complex protein Nup50; nuclear pore complex protein Nup50; LOW QUALITY PROTEIN: nuclear pore complex protein Nup50; nuclear pore complex protein nup50-like protein; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50; nucleoporin 50 kDa; Nucleoporin 50 kDa-like protein; nucleoporin 50kD; nucleoporin 50kDa; nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; Nup50; NUP50 protein; OTTHUMP00000199530; PRO1146; Rtp60; Unknown (protein for MGC:134469)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10762, 18141
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.79 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9JIH2, Q9UKX7
Gene Symbols:
NUP50
Immunogen:
Synthetic peptide corresponding to a region within amino acids 407 and 468 of Human NUP50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RNF2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNF2
Gene Alias: AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; DinG; DinG protein; E3 ubiquitin-protein ligase RING2; fa19h05; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; protein DinG; RING 1B; RING 2; RING finger protein 1B; ring finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; Rnf2; wu:fa19h05; wz4556; wz4566
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6045
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q99496
Gene Symbols: RNF2
Immunogen: Synthetic peptide corresponding to a region within amino acids 274 and 336 of Human RNF2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RNF2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNF2
Gene Alias:
AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; DinG; DinG protein; E3 ubiquitin-protein ligase RING2; fa19h05; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; protein DinG; RING 1B; RING 2; RING finger protein 1B; ring finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; Rnf2; wu:fa19h05; wz4556; wz4566
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6045
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q99496
Gene Symbols:
RNF2
Immunogen:
Synthetic peptide corresponding to a region within amino acids 274 and 336 of Human RNF2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CCNDBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCNDBP1
Gene Alias: AU022347; Ccndbp1; cyclin D1 binding protein 1; cyclin D-type binding-protein 1; cyclin-D1-binding protein 1; DIP1; D-type cyclin-interacting protein 1; GCIP; grap2 and cyclin D interacting protein; grap2 and cyclin-D-interacting protein; HHM; human homolog of Maid; Maid; Maternal Id-like protein; maternal inhibition of differentiation; SECC-8; SSEC-8; Stage specific embryonic cDNA-8 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23582
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O95273
Gene Symbols: CCNDBP1
Immunogen: Synthetic peptide corresponding to a region within amino acids 298 and 360 of Human CCNDBP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CCNDBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCNDBP1
Gene Alias:
AU022347; Ccndbp1; cyclin D1 binding protein 1; cyclin D-type binding-protein 1; cyclin-D1-binding protein 1; DIP1; D-type cyclin-interacting protein 1; GCIP; grap2 and cyclin D interacting protein; grap2 and cyclin-D-interacting protein; HHM; human homolog of Maid; Maid; Maternal Id-like protein; maternal inhibition of differentiation; SECC-8; SSEC-8; Stage specific embryonic cDNA-8 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23582
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O95273
Gene Symbols:
CCNDBP1
Immunogen:
Synthetic peptide corresponding to a region within amino acids 298 and 360 of Human CCNDBP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG