PIPA528584

SPHK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528584-Each-of-1 In Stock ₹ 44,790.66

PIPA528584 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

SPHK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9NYA1

Gene Symbols

SPHK1

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 220 of Human SPHK1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
  • Predicted reactivity: Human (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
  • Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
  • S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Compare Similar Items

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Img

Thermo Scientific

PIPA528584

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Antigen:
SPHK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8877

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 220 of Human SPHK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA528585

--


Antigen:
RIOK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIOK3

Gene Alias:
1200013N13Rik; D18Ertd331e; E130306C24Rik; homolog of the Aspergillus nidulans sudD gene product; RIO kinase 3; RIOK3; Serine/threonine-protein kinase RIO3; SUDD; sudD (suppressor of bimD6, Aspergillus nidulans) homolog; sudD homolog; sudD suppressor of Aspergillus nidulans bimD6 homolog; sudD suppressor of bimD6 homolog; sudD, suppressor of bimD6 homolog; testicular secretory protein Li 47

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361293, 66878, 8780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O14730, Q9DBU3

Gene Symbols:
RIOK3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 267 of Human RIOK3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA528587

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Antigen:
MAPK15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK15

Gene Alias:
BC048082; EC 2.7.11.24; ERK7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225689

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8TD08

Gene Symbols:
MAPK15

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 245 of Human MAPK15

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA528588

--


Antigen:
CCDC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCDC6

Gene Alias:
2810012H18Rik; AA536681; AA960498; AW061011; CCDC6; coiled-coil domain containing 6; coiled-coil domain-containing protein 6; D10S170; H4; Papillary thyroid carcinoma-encoded protein; Protein H4; PTC; TPC; TST1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8030

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.8 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q16204

Gene Symbols:
CCDC6

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 222 of Human CCDC6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG