PIPA528741

CXCR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528741-Each-of-1 In Stock ₹ 44,277.30

PIPA528741 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

CXCR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CXCR3

Gene Alias

an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2833

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P49682

Gene Symbols

CXCR3

Immunogen

Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CXCR3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: K562, NCI-H929
  • Predicted reactivity: Rhesus Monkey (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant)
  • IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues
  • Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration
  • Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein
  • Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors
  • As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration
  • Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface
  • This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues
  • In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells
  • Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases
  • Multiple transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA528741

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Antigen:
CXCR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXCR3

Gene Alias:
an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2833

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P49682

Gene Symbols:
CXCR3

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CXCR3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA528742

--


Antigen:
RORB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RORB

Gene Alias:
bA133M9.1; Nr1f2; Nuclear receptor ROR-beta; nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; RAR related orphan receptor B; RAR-related orphan receptor B; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor b; retinoid-related orphan receptor beta; retinoid-related orphan receptor-beta; ror beta; Rorb; Rorbeta; ROR-BETA; rzrb; RZR-beta; sb:eu943; transcription factor; Unknown (protein for IMAGE:7173671)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225998, 6096

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8R1B8, Q92753

Gene Symbols:
RORB

Immunogen:
Synthetic peptide corresponding to a region within amino acids 2 and 45 of ROR beta

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA528743

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Antigen:
CCRL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCRL2

Gene Alias:
1810047I05Rik; Ackr5; atypical chemokine receptor 5; C-C chemokine receptor-like 2; C-C motif chemokine receptor like 2; CCR11; CCR6; Ccrl2; chemokine (C-C motif) receptor-like 2; chemokine C-C motif receptor-like 2; chemokine C-C motif receptor-like 2-like; chemokine receptor CCR11; Chemokine receptor X; CKRX; Cmkbr1l2; CRAM; CRAM-A; CRAM-B; E01; G-protein coupled beta chemokine receptor; HCR; Lccr; L-CCR; Lipopolysaccharide-inducible C-C chemokine receptor; LOC100719164; MGC116710; Putative MCP-1 chemokine receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54199, 9034

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O00421, O35457

Gene Symbols:
CCRL2

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CCRL2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA528745

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Antigen:
HTR7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTR7

Gene Alias:
5-HT receptor 7a; 5-HT receptor 7b; 5Ht7; 5-HT7; 5-HT-7; 5HT7 Receptor; 5-HT7 receptor; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5-hydroxytryptamine receptor 7; GPRFO; high affinity serotonin receptor (5HT7); HT7; Htr7; OTTHUMP00000020077; OTTHUMP00000020078; OTTHUMP00000020079; Serotonin receptor 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3363

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P34969

Gene Symbols:
HTR7

Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human 5HT7 receptor

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG