PIPA529066

Complement C9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529066-Each-of-1 In Stock ₹ 44,790.66

PIPA529066 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

Complement C9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C9

Gene Alias

ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

735

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P02748

Gene Symbols

C9

Immunogen

Recombinant fragment corresponding to a region within amino acids 153 and 429 of Human C9

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA529731

--

Img

Thermo Scientific

PIPA529071

--

Img

Thermo Scientific

PIPA529097

--

Img

Thermo Scientific

PIPA529667

--

Img

Thermo Scientific

PIPA529126

--

Img

Thermo Scientific

PIPA528475

--

Img

Thermo Scientific

PIPA529137

--

Img

Thermo Scientific

PIPA529521

--

Description

  • Recommended positive controls: Jurkat
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • C5b-9 membrane attack complexes are assembled from five precursor molecules in the serum
  • Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 complex
  • The last step of C5b-9 complex formation involves polymerization of C9 which accompanies insertion of the complex into the cell membrane
  • During formation of C5b-8 and C9 polymerization, neoantigens are generated which are unique to the C5b-9 complex and are not present on any of the individual native complex components
  • The complement regulatory proteins CD59 and complement S-protein can both prevent C5b-9 insertion into the cell membrane
  • The formed SC5b-9 complex is unable to attach to cells and is cytolytically inactive
  • C5b-9 is involved in the progression of chronic proteinuric renal disease by mediating continuous tubulointerstitial damage
  • Early tubulointerstitial injury in the remnant kidney can be improved when C5b-9 complex forming is abrogated.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA529066

--


Antigen:
Complement C9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C9

Gene Alias:
ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
735

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P02748

Gene Symbols:
C9

Immunogen:
Recombinant fragment corresponding to a region within amino acids 153 and 429 of Human C9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529068

--


Antigen:
COL6A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Col6a1

Gene Alias:
AI747156; alpha 1 (VI) chain (61 AA); BTHLM1; Col6a1; Col6a-1; Collagen alpha-1(VI) chain; collagen type VI alpha 1; collagen type VI alpha 1 chain; collagen VI, alpha-1 polypeptide; collagen, type VI, alpha 1; OPLL; procollagen, type VI, alpha 1; RGD1565398; UCHMD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12833, 1291, 294337

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P12109, Q04857

Gene Symbols:
Col6a1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 552 and 826 of Human COL6A1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529070

--


Antigen:
SNW1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Snw1

Gene Alias:
2310008B08Rik; AW048543; Bx42; homolog of Drosophila BX42; NCOA-62; Nuclear protein SkiP; nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; PPS; Prp45; PRPF45; RGD1561926; SKI interacting protein; ski-interacting protein; Skiip; SKIP; SNW domain containing 1; SNW domain-containing protein 1; SNW1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22938, 66354

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.85 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13573, Q9CSN1

Gene Symbols:
Snw1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 239 and 516 of Human NCOA62

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529071

--


Antigen:
CFHR5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CFHR5

Gene Alias:
CFHL5; CFHR5; CFHR5D; complement factor H related 5; complement factor H-related 5; complement factor H-related protein 5; factor H-related protein 5; FHR5; FHR-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81494

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9BXR6

Gene Symbols:
CFHR5

Immunogen:
Recombinant fragment corresponding to a region within amino acids 238 and 519 of Human CFHR5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG