PIPA529136

alpha-ENaC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529136-Each-of-1 In Stock ₹ 47,015.22

PIPA529136 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

alpha-ENaC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCNN1A

Gene Alias

alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20276, 6337

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P37088, Q61180

Gene Symbols

SCNN1A

Immunogen

Recombinant fragment corresponding to a region within amino acids 272 and 555 of Human SCNN1A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, mouse kidney
  • Predicted reactivity: Mouse (84%), Rat (85%), Pig (85%), Rabbit (89%), Bovine (85%), Guinea pig (83%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
  • Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
  • There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
  • ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
  • ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
  • ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
  • Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA529136

--


Antigen:
alpha-ENaC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCNN1A

Gene Alias:
alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20276, 6337

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P37088, Q61180

Gene Symbols:
SCNN1A

Immunogen:
Recombinant fragment corresponding to a region within amino acids 272 and 555 of Human SCNN1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529137

--


Antigen:
TFR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tfr2

Gene Alias:
HFE3; MGC126368; TfR2; TFRC2; transferrin receptor 2; transferrin receptor protein 2; Trfr2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7036

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9UP52

Gene Symbols:
Tfr2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 287 and 565 of Human TFR2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529139

--


Antigen:
VPS33B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VPS33B

Gene Alias:
FLJ14848; hVPS33B; r-vps33b; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33 homolog B (yeast); vacuolar protein sorting 33B; vacuolar protein sorting 33B (yeast); vacuolar protein sorting 33-like protein B; vacuolar protein sorting homolog r-vps33b; vacuolar protein sorting-associated protein 33B; vacuolar sorting protein 33b; vps33b; VPS33B late endosome and lysosome associated; VPS33B, late endosome and lysosome associated; zgc:110803

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26276

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.97 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9H267

Gene Symbols:
VPS33B

Immunogen:
Recombinant fragment corresponding to a region within amino acids 224 and 502 of Human VPS33B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529140

--


Antigen:
TDG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TDG

Gene Alias:
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6996

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13569

Gene Symbols:
TDG

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 410 of Human TDG

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG