PIPA529225

TID1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529225-Each-of-1 In Stock ₹ 44,705.10

PIPA529225 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TID1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNAJA3

Gene Alias

1200003J13Rik; 1810053A11Rik; C81173; DnaJ (Hsp40) homolog, subfamily A, member 3; DnaJ heat shock protein family (Hsp40) member A3; dnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Dnaja3; HCA57; Hepatocellular carcinoma-associated antigen 57; hTID-1; mTid-1; Tid1; Tid-1; Tid1l; Tumorous imaginal discs protein Tid56 homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

360481, 9093

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q96EY1

Gene Symbols

DNAJA3

Immunogen

Recombinant fragment corresponding to a region within amino acids 172 and 438 of Human TID1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
  • Predicted reactivity: Mouse (94%), Rat (93%), Xenopus laevis (80%), Bovine (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • TID1 is a human homolog of the Drosophila tumor suppressor lethal (2) tumorous imaginal discs, l(2)tid and encodes two mitochondrial matrix localized splice variants of human Tid-1 designated hTid-1S and hTid-1L
  • These proteins are the conserved members of the DnaJ family of proteins which act as cochaperones for mitochondrial Hsp70
  • They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity
  • Expression of hTid-1L increases apoptosis induced by DNA damaging agents as mitomycin-C and TNF-a
  • A J-domain mutant of hTid-1L can dominantly suppress apoptosis and in sharp contrast the J-domain mutant of hTid-1S increases apoptosis
  • Expression of hTid-1S and hTid-1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected
  • It is strongly suggested that these two splice variants exert their anti- and pro- apoptotic effects through discrete substrates and activities
  • Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA529225

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Antigen:
TID1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJA3

Gene Alias:
1200003J13Rik; 1810053A11Rik; C81173; DnaJ (Hsp40) homolog, subfamily A, member 3; DnaJ heat shock protein family (Hsp40) member A3; dnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Dnaja3; HCA57; Hepatocellular carcinoma-associated antigen 57; hTID-1; mTid-1; Tid1; Tid-1; Tid1l; Tumorous imaginal discs protein Tid56 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
360481, 9093

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96EY1

Gene Symbols:
DNAJA3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 172 and 438 of Human TID1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529226

--


Antigen:
PPIL2 Isoform B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPIL2

Gene Alias:
CYC4; cyclophilin, 60kDa; cyclophilin-60; Cyclophilin-like protein Cyp-60; CYP60; Cyp-60; hCyP-60; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase-like 2; peptidylprolyl isomerase (cyclophilin)-like 2; peptidylprolyl isomerase like 2; PPIase; PPIL2; Probable inactive peptidyl-prolyl cis-trans isomerase-like 2; RING-type E3 ubiquitin-protein ligase PPIL2; Rotamase PPIL2; U-box domain containing 7; UBOX7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23759

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13356

Gene Symbols:
PPIL2

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 248 and 499 of Human PPIL2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA529227

--


Antigen:
IL1R1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il1r1

Gene Alias:
antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; il1 receptor; il-1 receptor; IL-1 receptor alpha chain; IL1R; il-1r; IL1R1; IL-1R1; IL-1R-1; Il1r-1; IL1RA; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; interleukin-1 receptor; interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3554

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P14778

Gene Symbols:
Il1r1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 342 and 558 of Human IL1 Receptor 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529229

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Antigen:
pro-EGF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGF

Gene Alias:
beta-urogastrone; Egf; Epidermal growth factor; HOMG4; Pro-epidermal growth factor; URG; Urogastrone

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1950, 25313

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P01133, P07522

Gene Symbols:
EGF

Immunogen:
Recombinant fragment corresponding to a region within amino acids 495 and 774 of Human pro-EGF

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG