PIPA529237

SMAD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529237-Each-of-1 In Stock ₹ 50,309.28

PIPA529237 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

SMAD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD2

Gene Alias

7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4087

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q15796

Gene Symbols

SMAD2

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 252 of Human SMAD2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, SMAD2-transfected 293T
  • Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (89%), Xenopus laevis (97%), Pig (85%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
  • SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
  • Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
  • In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
  • The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
  • The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
  • SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
  • Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

Compare Similar Items

Show Difference

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PIPA529237

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Antigen:
SMAD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4087

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q15796

Gene Symbols:
SMAD2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 252 of Human SMAD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA529240

--


Antigen:
DDX41

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX41

Gene Alias:
2900024F02Rik; AA958953; ABS; Abstrakt; AI324246; Ddx41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box helicase 41; DEAD-box protein abstrakt; MPLPF; probable ATP-dependent RNA helicase DDX41; putative RNA helicase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51428

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9UJV9

Gene Symbols:
DDX41

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 57 and 297 of Human DDX41

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529241

--


Antigen:
HSC70

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hspa8

Gene Alias:
2410008N15Rik; AAG2; constitutive heat shock protein 70; constitutively expressed heat shock protein; epididymis luminal protein 33; epididymis secretory sperm binding protein Li 72p; FAM10A1; Heat shock 70 kDa protein 8; heat shock 70kd protein 10; heat shock 70kd protein 10 (HSC71); heat shock 70kD protein 8; heat shock 70kDa protein 8; heat shock cognate; heat shock cognate 70; heat shock cognate 71 kD protein; heat shock cognate 71 kDa protein; heat shock cognate 71 kDa protein-like protein; heat shock cognate 71-kd protein; heat shock cognate hsc73; heat shock cognate protein 54; Heat shock cognate protein 70; heat shock protein 70 cognate; heat shock protein 8; heat shock protein A8; heat shock protein cognate 70; heat shock protein family A (Hsp70) member 8; HEL-33; HEL-S-72p; HIP; HSC54; Hsc70; Hsc70 ATPase; HSC70 protein; Hsc71; Hsc73; HSP70; HSP71; HSP73; Hspa10; Hspa8; hspa8 protein; I79_022974; LAP; LAP1; LAP-1; lipopolysaccharide-associated protein 1; LPS-associated protei

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100511890, 15481, 3312

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.79 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P11142, P63017

Gene Symbols:
Hspa8

Immunogen:
Recombinant fragment corresponding to a region within amino acids 341 and 565 of Human Hsc70

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG

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PIPA529242

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Antigen:
EEF1D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EEF1D

Gene Alias:
antigen NY-CO-4; EEF 1D; Eef1d; EF 1 delta; EF 1D; EF1D; EF-1D; EF-1-delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); FP1047; guanine nucleotide exchange protein; translation elongation factor 1-delta subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1936

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P29692

Gene Symbols:
EEF1D

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 310 and 281 of Human EEF1D

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG