PIPA529257

STEP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529257-Each-of-1 In Stock ₹ 45,646.26

PIPA529257 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

STEP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN5

Gene Alias

FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; PTPN5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19259, 84867

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.28 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P54829, P54830

Gene Symbols

PTPN5

Immunogen

Recombinant fragment corresponding to a region within amino acids 347 and 565 of Human STEP / PTPN5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, HepG2, mouse brain
  • Predicted reactivity: Mouse (95%), Rat (96%), Rhesus Monkey (98%), Bovine (96%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Reversible phosphorylation of tyrosine residues is a key regulatory mechanism for numerous cellular events such as proliferation, differentiation, gene expression and migration
  • Abnormalities in tyrosine phosphorylation play a role in the pathogenesis of numerous inherited or acquired human diseases from cancer to immune deficiencies
  • There are at least 107 genes coding for PTPs (protein tyrosine phosphatases) in the human genome
  • All known PTPs contain a highly conserved 12 amino acid catalytic domain and are further distinguished on the basis of additional structural motifs
  • The receptor-like PTPs exhibit an extracellular domain, a single transmembrane and one or two intracellular phosphatase domains
  • The nonreceptor cytoplasmic PTPs contain a single phosphatase domain and additional amino acid sequences that are homologous to motifs found in other classes of proteins
  • Protein tyrosine phosphatases PTPN5 (STEP), PTPRR and PTPN7 comprise a family of phosphatases that specifically inactivate MAPKs (mitogen-activated protein kinases)
  • There are multiple forms of STEP in the adult rat brain which show differential enrichment in brain regions implicated in aspects of cognitive, affective, and motor behaviors
  • Some of the STEP isoforms are generated through alternative splicing of a single STEP gene and each has unique intracellular targets and functions.

Compare Similar Items

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Img

Thermo Scientific

PIPA529257

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Antigen:
STEP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN5

Gene Alias:
FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; PTPN5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19259, 84867

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P54829, P54830

Gene Symbols:
PTPN5

Immunogen:
Recombinant fragment corresponding to a region within amino acids 347 and 565 of Human STEP / PTPN5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529259

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Antigen:
CIAPIN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIAPIN1

Gene Alias:
2810413N20Rik; AA617265; Anamorsin; anamorsin {ECO:0000255; AU021794; basic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix domain containing, class B2; basic helix-loop-helix family member e40; basic helix-loop-helix family, member e40; BHLHB2; Bhlhe40; C130042M06Rik; CIAPIN1; Class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; Clast5; CR8; CUA001; cytokine induced apoptosis inhibitor 1; cytokine response gene 8; cytokine-induced apoptosis inhibitor 1; cytokine-induced apoptosis inhibitor 1 {ECO:0000255; DEC1; differentially expressed in chondrocytes 1; differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; DRE2; E47 interaction protein 1; EIP1; eip1 (E47 interaction protein 1); enhancer-of-split and hairy-related protein 2; Fe-S cluster assembly protein DRE2 homolog; fe-S cluster assembly protein DRE2 homolog {ECO:0000255; HAMAP-Rule:MF_03115}; HLHB2; predicted protein of HQ0915;

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109006, 307649, 57019

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q5XID1, Q6FI81, Q8WTY4

Gene Symbols:
CIAPIN1

Immunogen:
Full length human CIAPIN1 Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA529261

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Antigen:
CARD10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD10

Gene Alias:
AI449026; Bcl10 binding protein and activator of NFKB; bcl10-interacting MAGUK protein 1; Bimp1; Card10; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Carma 3; Carma3; caspase recruitment domain family member 10; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
105844, 29775

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal, 0.025% ProClin 300; pH 7

Gene Accession No.:
P58660, Q9BWT7

Gene Symbols:
CARD10

Immunogen:
Recombinant fragment corresponding to a region within amino acids 341 and 630 of Human CARD10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529264

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Antigen:
CtBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTBP1

Gene Alias:
50 kDa BFA-dependent ADP-ribosylation substrate; 50-kDa BFA-induced ADP-ribosylated substrate; 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS; BARS-50; brefeldin A-ADP-riboslyated substrate; brefeldin A-ribosylated substrate; CTBP; CtBP1; CtBP1-L; CtBP1-S; CtBP3; CtBP3/BARS; C-terminal binding protein 1; C-terminal-binding protein 1; C-terminal-binding protein 3; C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate; D4S115h; D5H4S115; D5H4S115E; MGC104684

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13016, 1487

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.69 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O88712, Q13363

Gene Symbols:
CTBP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 84 and 329 of Human CtBP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG