PIPA529322

MEKK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529322-Each-of-1 In Stock ₹ 44,705.10

PIPA529322 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MEKK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Map3k3

Gene Alias

AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4215

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.72 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q99759

Gene Symbols

Map3k3

Immunogen

Recombinant fragment corresponding to a region within amino acids 210 and 488 of Human MEKK3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 3xFlag-human MAP3K3-transfected 293T
  • Predicted reactivity: Mouse (97%), Rat (97%), Rhesus Monkey (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks
  • Northern blot analysis revealed a 4
  • 6-kb transcript that appears to be ubiquitously expressed
  • This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway
  • In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA529322

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Antigen:
MEKK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Map3k3

Gene Alias:
AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4215

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.72 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99759

Gene Symbols:
Map3k3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 210 and 488 of Human MEKK3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA529323

--


Antigen:
TRIP6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIP6

Gene Alias:
MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP1; OIP-1; OPA-interacting protein 1; tcag7.1300; thyroid hormone receptor interacting protein 6; thyroid hormone receptor interactor 6; thyroid receptor-interacting protein 6; TR-interacting protein 6; Trip6; TRIP-6; TRIP6i2; Zrp1; ZRP-1; zyxin related protein 1; zyxin-related protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7205

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.82 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q15654

Gene Symbols:
TRIP6

Immunogen:
Recombinant fragment corresponding to a region within amino acids 162 and 454 of Human TRIP6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529326

--


Antigen:
HK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hk2

Gene Alias:
AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009677, 15277, 25059, 3099

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.76 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
A2PYL6, O08528, P27881, P52789

Gene Symbols:
Hk2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 53 and 342 of Human Hexokinase II

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Equine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA529328

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Antigen:
MARK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MARK3

Gene Alias:
1600015G02Rik; A430080F22Rik; cdc25C-associated protein kinase 1; cTAK1; C-TAK1; ELKL motif kinase 2; Emk2; EMK-2; EMK2/MARK3 serine-threonine protein kinase; ETK1; ETK-1; KP78; MAP/microtubule affinity regulating kinase 3; MAP/microtubule affinity-regulating kinase 3; MARK3; microtubule affinity regulating kinase 3; Mpk10; MPK-10; PAR1A; Par-1a; Protein kinase STK10; ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4140

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.99 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P27448

Gene Symbols:
MARK3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 411 and 740 of Human Mark3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG