PIPA529535

ERO1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529535-Each-of-1 In Stock ₹ 44,191.74

PIPA529535 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

ERO1L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERO1A

Gene Alias

Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

30001, 423585, 50527

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.95 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q96HE7

Gene Symbols

ERO1A

Immunogen

Recombinant fragment corresponding to a region within amino acids 99 and 410 of Human ERO1L

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Chicken, Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HCT116, MCF-7, mouse stomach
  • Predicted reactivity: Rat (90%), Pig (96%), Rhesus Monkey (99%), Bovine (96%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ERO1L (endoplasmic oxidoreductin-1-like protein) is localized in ER membrane as peripheral membrane protein on the lumenal side
  • Its association with ERP44 is essential for its retention in the ER and is unique in coupling oxygen reduction to de novo disulfides formation
  • The ERO1L enzyme is broadly distributed at low levels in several tissues with highest levels in the upper digestive tract and is stimulated by hypoxia via HIF-signaling
  • ERO1L generally exists as monomer, but has the ability to function as monomer or homodimer and interacts with PDILT
  • After translation, ERO1L gets n-glycosylated and the disulfide bonds constitute the redox-active center whereby the Cys-94/Cys-99 disulfide bond accepts an electron from P4HB followed by funneling the same to the active site disulfide Cys-394/Cys-397
  • ERO1L acts by oxidizing directly to P4HB/PDI isomerase through direct disulfide exchange and associates with ERP44
  • ERO1L is implicated in immunoglobulin folding, oxidative stress, release of unfolded cholera toxin from reduced P4HB/PDI upon Vibrio cholerae infection, and plays a key role in ER stress-induced CHOP-dependent apoptosis through inositol 1,4,5-trisphosphate receptor IP3R1 activation.

Compare Similar Items

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PIPA529535

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Antigen:
ERO1L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERO1A

Gene Alias:
Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30001, 423585, 50527

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.95 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96HE7

Gene Symbols:
ERO1A

Immunogen:
Recombinant fragment corresponding to a region within amino acids 99 and 410 of Human ERO1L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529537

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Antigen:
Cdc5L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC5L

Gene Alias:
1200002I02Rik; AA408004; CDC5; CDC5 cell division cycle 5-like; CDC5 cell division cycle 5-like (S. pombe); CDC5L; CDC5-LIKE; Cdc5-like protein; Cdc5-related protein; CEF1; cell division cycle 5 like; cell division cycle 5-like; cell division cycle 5-like (S. pombe); cell division cycle 5-like protein; cell division cycle 5-related protein; dJ319D22.1; dJ319D22.1 (CDC5-like protein); hCDC5; KIAA0432; Pcdc5rp; Pombe cdc5-related protein; Unknown (protein for MGC:128482); zgc:55853

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71702, 988

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.22 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q6A068, Q99459

Gene Symbols:
CDC5L

Immunogen:
Recombinant fragment corresponding to a region within amino acids 262 and 536 of Human CDC5L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529539

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Antigen:
HSPA4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSPA4

Gene Alias:
70kDa; AI317151; APG2; APG-2; epididymis secretory sperm binding protein Li 5a; heat shock 70 kDa protein 4; heat shock 70kD protein 4; heat shock 70kDa protein 4; Heat shock 70-related protein APG-2; Heat shock protein; heat shock protein 4; heat shock protein Apg-2; heat shock protein family A (Hsp70) member 4; heat shock protein, 110 kDa; HEL-S-5a; HS24/P52; Hsp110; hsp70; hsp70 RY; Hsp70RY; Hspa4; HSPH2; Irp94; ischemia responsive 94 kDa protein; mKIAA4025; RY

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15525, 3308

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P34932, Q61316

Gene Symbols:
HSPA4

Immunogen:
Recombinant fragment corresponding to a region within amino acids 288 and 568 of Human HSPA4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529540

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Antigen:
eIF4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eif4b

Gene Alias:
2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1975, 75705

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.16 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P23588, Q8BGD9

Gene Symbols:
Eif4b

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 198 of Human EIF4B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG