PIPA529799

Cortactin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529799-Each-of-1 In Stock ₹ 49,582.02

PIPA529799 - Each of 1

₹ 49,582.02

In Stock

Quantity

1

Base Price: ₹ 49,582.02

GST (18%): ₹ 8,924.764

Total Price: ₹ 58,506.784

Antigen

Cortactin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cttn

Gene Alias

1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13043, 2017, 60465

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.28 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q14247, Q60598, Q66HL2

Gene Symbols

Cttn

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 276 of Human Cortactin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, Neuro 2A, C8D30, NIH-3T3, C2C12, PC-12, Rat2, mouse brain, rat brain
  • Predicted reactivity: Mouse (98%), Rat (99%), Chicken (93%), Rhesus Monkey (100%), Bovine (85%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Cortactin (Cttn) is a ubiquitous actin-binding protein that was originally identified as a substrate for Src
  • It contributes to the organization of the actin cytoskeleton and cell shape
  • Cortactin also plays a role in the formation of lamellipodia and cell migration
  • It is accumulated in peripheral, actin-enriched structures of cells suggesting that cortactin facilitates actin network formation
  • Cortactin has four major domains of interest the N-terminal acidic (NTA) and tandem repeats domains and the C-terminal proline-rich and SH3 Domains
  • NTA associates with the Arp2/3 and WASP complex at F-actin branches
  • Cortactin is involved in promoting cell motility and invasion, including a critical role in invadopodia, actin rich-subcellular protrusions associated with degradation of the ECM by cancer cells
  • Cortactin is phosphorylated by src family kinases at Y421, Y466, and Y482 and S405 and S418 that are phosphorylated by Erk family kinases.

Compare Similar Items

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Thermo Scientific

PIPA529799

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Antigen:
Cortactin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cttn

Gene Alias:
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13043, 2017, 60465

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q14247, Q60598, Q66HL2

Gene Symbols:
Cttn

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 276 of Human Cortactin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA529800

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Antigen:
IRE1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2081, 417414

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.5 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O75460

Gene Symbols:
ERN1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 224 of Human IRE1 alpha

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529801

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Antigen:
Fibrillarin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
fbl

Gene Alias:
34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AL022665; AT20009p; CELE_T01C3.7; CG5725; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; Fbl; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; FIB; FIB1; fib-1; fibrillarin; FLRN; fumble; histone-glutamine methyltransferase; LD24618p; LP11571p; nucleolar protein 1; PANK; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; RNU3IP1; rRNA 2'-O-methyltransferase fibrillarin; T01C3.7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14113, 2091, 292747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.36 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P22087, P22509, P35550

Gene Symbols:
fbl

Immunogen:
Recombinant fragment corresponding to a region within amino acids 75 and 321 of Human Fibrillarin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA529803

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Antigen:
CD23

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FCER2

Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2208

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P06734

Gene Symbols:
FCER2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 123 and 321 of Human CD23

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG