PIPA529825
MBNL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529825-Each-of-1 | In Stock | ₹ 47,785.26 |
PIPA529825 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,785.26
GST (18%): ₹ 8,601.347
Total Price: ₹ 56,386.607
Antigen
MBNL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MBNL1
Gene Alias
DKFZp686P06174; EXP; EXP35; EXP40; EXP42; KIAA0428; MBNL; MBNL1; mKIAA0428; muscleblind like splicing regulator 1; muscleblind-like 1; muscleblind-like 1 (Drosophila); muscleblind-like protein 1; muscleblind-like splicing regulator 1; triplet-expansion RNA-binding protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4154
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.45 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NR56
Gene Symbols
MBNL1
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 259 of Human Muscleblind-like 1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, HeLa, Jurkat
- Predicted reactivity: Mouse (98%), Rat (99%), Chicken (97%), Bovine (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- EGFR (Epidermal growth factor receptor, HER1, ErbB1) is encoded by the EGFR gene located on chromosome 7 in humans
- EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4
- EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain
- Phosphorylation of EGFR at certain residues is also mediated by Src-non-receptor kinase
- EGFR activation signals multiple downstream signaling cascades such as the Ras - ERK, PI3-K - Akt, Jak - STAT and PKC pathways that help in growth and proliferation of cells
- Phosphorylation of EGFR at Y1086 specifically allows binding of the adaptor protein GRB2, leading to activation of the MAPK pathway
- Upon receptor activation and signaling, EGFR is endocytosed and targeted for degradation or recycling
- Mutations in the EGFR gene are associated with lung cancer and multiple alternatively spliced transcript variants encode different protein isoforms of EGFR have been found
- Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors
- Moreover, EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Compare Similar Items
Show Difference
Antigen: MBNL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MBNL1
Gene Alias: DKFZp686P06174; EXP; EXP35; EXP40; EXP42; KIAA0428; MBNL; MBNL1; mKIAA0428; muscleblind like splicing regulator 1; muscleblind-like 1; muscleblind-like 1 (Drosophila); muscleblind-like protein 1; muscleblind-like splicing regulator 1; triplet-expansion RNA-binding protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4154
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.45 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NR56
Gene Symbols: MBNL1
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 259 of Human Muscleblind-like 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MBNL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MBNL1
Gene Alias:
DKFZp686P06174; EXP; EXP35; EXP40; EXP42; KIAA0428; MBNL; MBNL1; mKIAA0428; muscleblind like splicing regulator 1; muscleblind-like 1; muscleblind-like 1 (Drosophila); muscleblind-like protein 1; muscleblind-like splicing regulator 1; triplet-expansion RNA-binding protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4154
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.45 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NR56
Gene Symbols:
MBNL1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 259 of Human Muscleblind-like 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MLK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K9
Gene Alias: E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4293
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.4 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P80192
Gene Symbols: MAP3K9
Immunogen: Recombinant fragment corresponding to a region within amino acids 198 and 433 of Human MLK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MLK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K9
Gene Alias:
E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4293
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.4 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P80192
Gene Symbols:
MAP3K9
Immunogen:
Recombinant fragment corresponding to a region within amino acids 198 and 433 of Human MLK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MSH3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MSH3
Gene Alias: D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4437
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.79 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P20585
Gene Symbols: MSH3
Immunogen: Recombinant protein fragment corresponding to a region within amino acids 916 and 1137 of Human MSH3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MSH3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MSH3
Gene Alias:
D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4437
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.79 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P20585
Gene Symbols:
MSH3
Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 916 and 1137 of Human MSH3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PRDX1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRDX1
Gene Alias: ACR1; Alu co-repressor 1; AOEB166; B166; HBP23; heme-binding 23 kDa protein; macrophage 23 Kd stress protein; macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; Msp23; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NkefA; NKEF-A; OSF3; OSF-3; osteoblast specific factor 3; osteoblast-specific factor 3; PAG; Paga; PAGB; peroxiredoxin 1; peroxiredoxin-1; PRDX1; PrdxI; proliferation-associated gene A; proliferation-associated gene protein; Prx; Prx 1; PRX1; PRXI; TDPX2; TDX2; thioredoxin dependent peroxide reductase 2; thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; TPxA; Trx dependent peroxide reductase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18477, 5052
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.57 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P35700, Q06830
Gene Symbols: PRDX1
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 199 of Human PRX I
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PRDX1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRDX1
Gene Alias:
ACR1; Alu co-repressor 1; AOEB166; B166; HBP23; heme-binding 23 kDa protein; macrophage 23 Kd stress protein; macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; Msp23; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NkefA; NKEF-A; OSF3; OSF-3; osteoblast specific factor 3; osteoblast-specific factor 3; PAG; Paga; PAGB; peroxiredoxin 1; peroxiredoxin-1; PRDX1; PrdxI; proliferation-associated gene A; proliferation-associated gene protein; Prx; Prx 1; PRX1; PRXI; TDPX2; TDX2; thioredoxin dependent peroxide reductase 2; thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; TPxA; Trx dependent peroxide reductase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18477, 5052
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.57 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P35700, Q06830
Gene Symbols:
PRDX1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 199 of Human PRX I
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG