PIPA529847
TRPC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529847-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA529847 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TRPC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Trpc6
Gene Alias
AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22068, 7225, 89823
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.84 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q61143, Q9Y210
Gene Symbols
Trpc6
Immunogen
Recombinant fragment corresponding to a region within amino acids 121 and 458 of Human TRPC6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, A549 membrane fraction extract
- Predicted reactivity: Mouse (96%), Rat (95%), Bovine (96%), Guinea pig (97%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Trpc6 forms a receptor-activated calcium channel in the cell membrane
- The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
- Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
- Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
- Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "ecanonical TRP"e (TRPC) family
- The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
- Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
- When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
- Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
- There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
- Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.
Compare Similar Items
Show Difference
Antigen: TRPC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Trpc6
Gene Alias: AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22068, 7225, 89823
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.84 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q61143, Q9Y210
Gene Symbols: Trpc6
Immunogen: Recombinant fragment corresponding to a region within amino acids 121 and 458 of Human TRPC6
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TRPC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Trpc6
Gene Alias:
AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22068, 7225, 89823
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.84 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q61143, Q9Y210
Gene Symbols:
Trpc6
Immunogen:
Recombinant fragment corresponding to a region within amino acids 121 and 458 of Human TRPC6
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: WARS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WARS1
Gene Alias: GAMMA-2; hWRS; IFI 53; IFI53; IFP 53; IFP53; Interferon-induced protein 53; T1-TrpRS; T2-TrpRS; TrpRS; tryptophan tRNA ligase 1, cytoplasmic; tryptophan--tRNA ligase, cytoplasmic; Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, cytoplasmic; Wars; WARS protein; Wrs
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22375, 7453
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P23381, P32921
Gene Symbols: WARS1
Immunogen: Recombinant fragment corresponding to a region within amino acids 176 and 451 of Human Tryptophanyl tRNA synthetase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
WARS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WARS1
Gene Alias:
GAMMA-2; hWRS; IFI 53; IFI53; IFP 53; IFP53; Interferon-induced protein 53; T1-TrpRS; T2-TrpRS; TrpRS; tryptophan tRNA ligase 1, cytoplasmic; tryptophan--tRNA ligase, cytoplasmic; Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, cytoplasmic; Wars; WARS protein; Wrs
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22375, 7453
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P23381, P32921
Gene Symbols:
WARS1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 176 and 451 of Human Tryptophanyl tRNA synthetase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SRC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCOA3
Gene Alias: 2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8202
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9Y6Q9
Gene Symbols: NCOA3
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 246 of Human NCOA3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SRC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCOA3
Gene Alias:
2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8202
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9Y6Q9
Gene Symbols:
NCOA3
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 246 of Human NCOA3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Cullin 4A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUL4A
Gene Alias: 2810470J21Rik; AW495282; CUL 4A; Cul4a; CUL-4A; Cul4a protein; cullin 4A; cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753; RGD1563853
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8451
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13619
Gene Symbols: CUL4A
Immunogen: Recombinant fragment corresponding to a region within amino acids 119 and 385 of Human Cullin 4a
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cullin 4A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUL4A
Gene Alias:
2810470J21Rik; AW495282; CUL 4A; Cul4a; CUL-4A; Cul4a protein; cullin 4A; cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753; RGD1563853
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8451
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13619
Gene Symbols:
CUL4A
Immunogen:
Recombinant fragment corresponding to a region within amino acids 119 and 385 of Human Cullin 4a
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG