PIPA529879

HP1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA529879-Each-of-1 In Stock ₹ 45,560.70

PIPA529879 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

HP1 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cbx5

Gene Alias

2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12419, 23468

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P45973, Q61686

Gene Symbols

Cbx5

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 138 of Human HP1 alpha

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, HeLa nucleus
  • Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (80%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA529879

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Antigen:
HP1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cbx5

Gene Alias:
2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12419, 23468

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P45973, Q61686

Gene Symbols:
Cbx5

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 138 of Human HP1 alpha

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529880

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Antigen:
PADI4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Padi4

Gene Alias:
HL-60 PAD; PAD; PAD type IV; PAD4; Padi4; PADI5; PADI-H protein; PAD-R4; Pdi4; PDI5; peptidyl arginine deiminase 4; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; peptidylarginine deiminase IV; Peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; Protein-arginine deiminase type-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9UM07

Gene Symbols:
Padi4

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 8 and 203 of Human PAD4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529881

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Antigen:
RAD54B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD54B

Gene Alias:
DNA repair and recombination protein RAD54B; E130016E03Rik; fibrinogen silencer-binding protein; FSBP; LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54B; RAD54 homolog B; RAD54 homolog B (S. cerevisiae); RAD54, S. cerevisiae, homolog of, B; Rad54b; RDH54; RGD1306507

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25788

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9Y620

Gene Symbols:
RAD54B

Immunogen:
Recombinant fragment corresponding to a region within amino acids 48 and 291 of Human RAD54B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529882

--


Antigen:
BACE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BACE2

Gene Alias:
1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25825, 288227

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.83 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q6IE75, Q9Y5Z0

Gene Symbols:
BACE2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 319 and 518 of Human BACE2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG