PIPA529939
Calcineurin B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529939-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA529939 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
Calcineurin B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP3R1
Gene Alias
ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19058, 29748, 5534
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.76 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P63098, P63100, Q63810
Gene Symbols
PPP3R1
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 154 of Human Calcineurin B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse fetal brain, rat brain, MEF
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (97%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Calcineurin is a Ser/Thr, calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway
- Calcineurin (also referred to as protein phosphatase 2B) is composed of two subunits; calcineurin A (CnA), a 60 kDa catalytic subunit which is highly homologous to protein phosphatases 1 and 2A; and a 19 kDa regulatory subunit, calcineurin B (CnB) which, like calmodulin, contains four EF-hand calcium binding sites
- Calcineurin-mediated dephosphorylation of the nuclear factor of activated T-cells (NF-AT) is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells
- The immunosuppressive drugs, cyclosporin A and FK506, when bound to the immunophilins, cyclophilin and FKBP respectively, inhibit dephosphorylation and activation of NF-AT by calcineurin
- This inhibition is caused by the immunosuppressant/immunophilin complex simultaneously binding to both CnA and CnB which does not inhibit the phosphatase activity of CnA, but rather blocks access of the substrate to the catalytic domain of CnA.
Compare Similar Items
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Antigen: Calcineurin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP3R1
Gene Alias: ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19058, 29748, 5534
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.76 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P63098, P63100, Q63810
Gene Symbols: PPP3R1
Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 154 of Human Calcineurin B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Calcineurin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP3R1
Gene Alias:
ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19058, 29748, 5534
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.76 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P63098, P63100, Q63810
Gene Symbols:
PPP3R1
Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 154 of Human Calcineurin B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZDHHC17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZDHHC17
Gene Alias: A230053P19Rik; BB187739; D130071N24Rik; DHHC-17; Hip14; HIP-14; HIP3; HIP-3; HSPC294; huntingtin interacting protein 14; huntingtin interacting protein 3; Huntingtin interacting protein H; huntingtin yeast partner H; Huntingtin-interacting protein 14; huntingtin-interacting protein 3; Huntingtin-interacting protein H; HYPH; Kiaa0946; membrane-associated DHHC17 zinc finger protein; palmito; palmitoyltransferase ZDHHC17; Putative MAPK-activating protein PM11; putative NF-kappa-B-activating protein 205; ZDHHC17; Zinc finger DHHC domain-containing protein 17; zinc finger DHHC-type containing 17; zinc finger, DHHC domain containing 17; zinc finger, DHHC-type containing 17
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23390, 320150
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q80TN5, Q8IUH5
Gene Symbols: ZDHHC17
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 276 of Human ZDHHC17
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ZDHHC17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZDHHC17
Gene Alias:
A230053P19Rik; BB187739; D130071N24Rik; DHHC-17; Hip14; HIP-14; HIP3; HIP-3; HSPC294; huntingtin interacting protein 14; huntingtin interacting protein 3; Huntingtin interacting protein H; huntingtin yeast partner H; Huntingtin-interacting protein 14; huntingtin-interacting protein 3; Huntingtin-interacting protein H; HYPH; Kiaa0946; membrane-associated DHHC17 zinc finger protein; palmito; palmitoyltransferase ZDHHC17; Putative MAPK-activating protein PM11; putative NF-kappa-B-activating protein 205; ZDHHC17; Zinc finger DHHC domain-containing protein 17; zinc finger DHHC-type containing 17; zinc finger, DHHC domain containing 17; zinc finger, DHHC-type containing 17
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23390, 320150
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q80TN5, Q8IUH5
Gene Symbols:
ZDHHC17
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 276 of Human ZDHHC17
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TDP-43
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TARDBP
Gene Alias: 1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 230908, 23435, 298648
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.63 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q13148, Q921F2
Gene Symbols: TARDBP
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 289 of Human TARDBP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TDP-43
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TARDBP
Gene Alias:
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
230908, 23435, 298648
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q13148, Q921F2
Gene Symbols:
TARDBP
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 289 of Human TARDBP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PACT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRKRA
Gene Alias: AV120107; DYT16; HSD14; HSD-14; interferon-inducible double stranded RNA-dependent protein kinase activator A; interferon-inducible double-stranded RNA-dependent protein kinase activator A; lear; PACT; PKR associated protein X; PKR-associated protein X; PKR-associating protein X; PRK; PRKRA; protein activator of interferon induced protein kinase EIF2AK2; protein activator of the interferon-induced protein kinase; protein kinase, interferon inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA-dependent activator; protein kinase, interferon-inducible double-stranded RNA-dependent activator; RAX
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8575
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.51 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O75569
Gene Symbols: PRKRA
Immunogen: Recombinant fragment corresponding to a region within amino acids 88 and 313 of Human PACT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Amphibian, Human
Product Type: Antibody
Isotype: IgG
Antigen:
PACT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRKRA
Gene Alias:
AV120107; DYT16; HSD14; HSD-14; interferon-inducible double stranded RNA-dependent protein kinase activator A; interferon-inducible double-stranded RNA-dependent protein kinase activator A; lear; PACT; PKR associated protein X; PKR-associated protein X; PKR-associating protein X; PRK; PRKRA; protein activator of interferon induced protein kinase EIF2AK2; protein activator of the interferon-induced protein kinase; protein kinase, interferon inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA-dependent activator; protein kinase, interferon-inducible double-stranded RNA-dependent activator; RAX
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8575
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.51 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O75569
Gene Symbols:
PRKRA
Immunogen:
Recombinant fragment corresponding to a region within amino acids 88 and 313 of Human PACT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Amphibian, Human
Product Type:
Antibody
Isotype:
IgG