PIPA530056

HAS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA530056-Each-of-1 In Stock ₹ 45,560.70

PIPA530056 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

HAS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HAS3

Gene Alias

HA synthase 3; Has3; Hyaluronan synthase 3; hyaluronate synthase 3; Hyaluronic acid synthase 3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3038

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.89 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O00219

Gene Symbols

HAS3

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 44 and 250 of Human HAS3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: NT2D1, PC-3, SK-N-SH
  • Predicted reactivity: Mouse (94%), Rat (95%), Pig (97%), Rabbit (97%), Rhesus Monkey (96%), Bovine (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • HAS1, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins
  • The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1,3 and b-1,4 glycosidic bonds
  • The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix
  • Both HAS1 and HAS2 synthesize high molecular-weight HA, whereas HAS3 produces lower molecular weight HA
  • The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins
  • HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults
  • HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis
  • Specifically, IFN-g markedly upregulates HAS3 mRNA, whereas TGFbeta downregulates HAS3 transcript levels
  • The human HAS3 gene maps to chromosome 16q22
  • 1.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA530056

--


Antigen:
HAS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HAS3

Gene Alias:
HA synthase 3; Has3; Hyaluronan synthase 3; hyaluronate synthase 3; Hyaluronic acid synthase 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3038

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.89 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O00219

Gene Symbols:
HAS3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 44 and 250 of Human HAS3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA530057

--


Antigen:
HCLS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HCLS1

Gene Alias:
AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3059

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.95 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P14317

Gene Symbols:
HCLS1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 221 of Human HCLS1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA530058

--


Antigen:
HIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBE2K

Gene Alias:
AW492011; D5Ertd601e; DKFZp564C1216; DKFZp686J24237; E2 ubiquitin-conjugating enzyme K; E2(25K); E2-25k; HIP2; HIP-2; huntingtin interacting protein 2; huntingtin-interacting protein 2; HYPG; LIG; UBC1; UBE2K; Ubiquitin carrier protein; ubiquitin conjugating enzyme E2 K; ubiquitin conjugating enzyme E2K; ubiquitin-conjugating enzyme E2 K; Ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2K; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); ubiquitin-protein ligase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3093, 53323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P61086, P61087

Gene Symbols:
UBE2K

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 167 of Human HIP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA530059

--


Antigen:
HMGCL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGCL

Gene Alias:
3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; AW476067; HL; Hmgcl; HMG-CoA lyase; hydroxymethylglutaricaciduria; hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3155

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.44 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P35914

Gene Symbols:
HMGCL

Immunogen:
Recombinant fragment corresponding to a region within amino acids 69 and 290 of Human HMGCL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG