PIPA530397

RGS14 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530397-Each-of-1 In Stock ₹ 46,159.62

PIPA530397 - Each of 1

₹ 46,159.62

In Stock

Quantity

1

Base Price: ₹ 46,159.62

GST (18%): ₹ 8,308.732

Total Price: ₹ 54,468.352

Antigen

RGS14

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rgs14

Gene Alias

rap1/rap2 interacting protein; RAP1/RAP2-interacting protein; Regulator of G-protein signaling 14; regulator of G-protein signalling 14; RGS14; RGSE; RPIP1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10636, 51791

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.7 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O43566, P97492

Gene Symbols

Rgs14

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 193 of Human RGS14

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, Jurkat, Raji
  • Predicted reactivity: Mouse (91%), Rat (90%), Bovine (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • RGS14 is a member of the regulator of G-protein signaling family which contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain
  • RGS14 attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits
  • Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP
  • The resulting hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal
  • Alternate transcriptional splice variants of RGS14 have been observed but have not been thoroughly characterized
  • Further, RGS14 acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism; plays a role in cell division; is required for the nerve growth factor (NGF)-mediated neurite outgrowth, and is involved in stress resistance
  • RGS14 protein may also be involved in visual memory processing capacity and hippocampal-based learning and memory.

Compare Similar Items

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Thermo Scientific

PIPA530397

--


Antigen:
RGS14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rgs14

Gene Alias:
rap1/rap2 interacting protein; RAP1/RAP2-interacting protein; Regulator of G-protein signaling 14; regulator of G-protein signalling 14; RGS14; RGSE; RPIP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10636, 51791

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.7 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O43566, P97492

Gene Symbols:
Rgs14

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 193 of Human RGS14

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA530404

--


Antigen:
GRAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRAP

Gene Alias:
8430435N19Rik; BB233594; GRAP; GRB2 related adaptor protein; GRB2-related adapter protein; GRB2-related adaptor protein; growth factor receptor-bound protein 2-related adaptor protein; MGC64880

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10750, 71520

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13588, Q9CX99

Gene Symbols:
GRAP

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 202 of Human GRAP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA530406

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Antigen:
NCKAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCKAP1

Gene Alias:
Brain protein H19; C79304; H19; HEM2; Hem-2; KIAA0587; Membrane-associated protein HEM-2; MH19; mKIAA0587; NAP 1; Nap1; NAP125; NCK associated protein 1; NCKAP1; NCK-associated protein 1; p125Nap1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10787, 50884

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.36 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P28660, Q9Y2A7

Gene Symbols:
NCKAP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 2 and 338 of Human NCKAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA530407

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Antigen:
MTHFD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTHFD2

Gene Alias:
AW558851; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 2; Mthfd2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10797, 17768, 680308

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.61 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P13995, P18155

Gene Symbols:
MTHFD2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 141 and 350 of Human MTHFD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG