PIPA530655

CHFR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530655-Each-of-1 In Stock ₹ 44,705.10

PIPA530655 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CHFR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chfr

Gene Alias

5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55743

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q96EP1

Gene Symbols

Chfr

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 351 and 538 of Human CHFR

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T
  • Predicted reactivity: Human (99%), Mouse (85%), Rat (84%), Bovine (81%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons
  • Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus
  • Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome
  • Promotes the ubiquitination and subsequent degradation of AURKA and PLK1
  • Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation
  • May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer
  • Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA530655

--


Antigen:
CHFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chfr

Gene Alias:
5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55743

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96EP1

Gene Symbols:
Chfr

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 351 and 538 of Human CHFR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA530657

--


Antigen:
ZNF434

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZSCAN32

Gene Alias:
HCCS5; HCCS-5; Human cervical cancer suppressor gene 5 protein; zinc finger and SCAN domain containing 32; zinc finger and SCAN domain-containing protein 32; Zinc finger protein 434; ZNF434; ZSCAN32

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54925

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9NX65

Gene Symbols:
ZSCAN32

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 64 and 237 of Human ZNF434

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA530661

--


Antigen:
USP47

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP47

Gene Alias:
4930502N04Rik; A630020C16Rik; deubiquitinating enzyme 47; Trf (TATA binding protein-related factor)-proximal homolog; TRFP; Ubiquitin carboxyl-terminal hydrolase 47; ubiquitin specific peptidase 47; ubiquitin specific protease 47; ubiquitin thioesterase 47; ubiquitin thiolesterase 47; ubiquitin-specific-processing protease 47; Usp47

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55031, 74996

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.54 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8BY87, Q96K76

Gene Symbols:
USP47

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1186 and 1375 of Human USP47

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA530662

--


Antigen:
MOCOS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MOCOS

Gene Alias:
1110018O12Rik; HMCS; MCS; moCo sulfurase; MOCOS; Molybdenum cofactor sulfurase; molybdenum cofactor sulfurtransferase; MOS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55034

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96EN8

Gene Symbols:
MOCOS

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 283 of Human MOCOS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG