PIPA530823

GSDMD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530823-Each-of-1 In Stock ₹ 47,528.58

PIPA530823 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

GSDMD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSDMD

Gene Alias

1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79792

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.24 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P57764

Gene Symbols

GSDMD

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 200 of Human GSDMD

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: A431
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • GSDMD (gasdermin-D) promotes pyroptosis in response to microbial infection and danger signals
  • It is produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as, non-canonical (such as cytosolic LPS) inflammasome activators
  • After cleavage, GSDMD moves to the plasma membrane where it strongly binds to inner leaflet lipids including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-biphosphate, phosphatidylinositol (3,4,5)-biphosphate, phosphatidic acid, and phosphatidylserine
  • GSDMD also exhibits bactericidal activity.

Compare Similar Items

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Img

Thermo Scientific

PIPA530823

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Antigen:
GSDMD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.24 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P57764

Gene Symbols:
GSDMD

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 200 of Human GSDMD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA530827

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Antigen:
HPS6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hps6

Gene Alias:
5330434M19Rik; BLOC2; BLOC2S3; FLJ22501; Hermansky-Pudlak syndrome 6; Hermansky-Pudlak syndrome 6 protein; Hermansky-Pudlak syndrome 6 protein homolog; Hermansky-Pudlak syndrome-6 protein (HPS6); Hps6; HPS6, biogenesis of lysosomal organelles complex 2 subunit 3; Hsp6; MGC20522; RP11-302K17.1; ru; ruby eye; ruby-eye protein; Ruby-eye protein homolog; ruby-eye-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79803

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.95 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q86YV9

Gene Symbols:
Hps6

Immunogen:
Recombinant fragment corresponding to a region within amino acids 189 and 459 of Human HPS6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA530828

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Antigen:
PYGO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYGO2

Gene Alias:
1190004M21Rik; mpygo2; PP7910; PYGO2; pygopus 2; pygopus family PHD finger 2; pygopus homolog 2; RGD1308535

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
90780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9BRQ0

Gene Symbols:
PYGO2

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 190 and 385 of Human Pygopus 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA530830

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Antigen:
ZNF671

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF671

Gene Alias:
Zinc finger protein 671; ZNF671

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79891

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8TAW3

Gene Symbols:
ZNF671

Immunogen:
Recombinant fragment corresponding to a region within amino acids 11 and 315 of Human ZNF671

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG