PIPA530972
RRP4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530972-Each-of-1 | In Stock | ₹ 45,560.70 |
PIPA530972 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,560.70
GST (18%): ₹ 8,200.926
Total Price: ₹ 53,761.626
Antigen
RRP4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EXOSC2
Gene Alias
EXOSC2; Exosome complex component RRP4; exosome complex exonuclease RRP4; exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; Ribosomal RNA-processing protein 4; RRP4; Rrp4p
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23404
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q13868
Gene Symbols
EXOSC2
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 277 of Human RRP4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (80%), Xenopus laevis (84%), Chicken (90%), Bovine (96%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
- In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
- The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
- In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
- It seems to be involved in degradation of histone mRNA
- The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes
- EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7
- [UniProt]
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Antigen: RRP4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXOSC2
Gene Alias: EXOSC2; Exosome complex component RRP4; exosome complex exonuclease RRP4; exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; Ribosomal RNA-processing protein 4; RRP4; Rrp4p
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23404
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13868
Gene Symbols: EXOSC2
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 277 of Human RRP4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RRP4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXOSC2
Gene Alias:
EXOSC2; Exosome complex component RRP4; exosome complex exonuclease RRP4; exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; Ribosomal RNA-processing protein 4; RRP4; Rrp4p
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23404
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13868
Gene Symbols:
EXOSC2
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 277 of Human RRP4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NUDC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUDC
Gene Alias: c15; clone 15; H M NPD011; HNUDC; MNUDC; MNUDC protein; NPD011; nuclear distribution C homolog; nuclear distribution C, dynein complex regulator; nuclear distribution gene C homolog; nuclear distribution gene C homolog (Aspergillus); nuclear distribution protein C homolog; Nuclear migration protein nudC; Nudc; nudC nuclear distribution protein; OTTHUMP00000004405; SIG-92; Silg92; silica-induced gene 92 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10726, 18221
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O35685, Q9Y266
Gene Symbols: NUDC
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 260 of Human NUDC
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NUDC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUDC
Gene Alias:
c15; clone 15; H M NPD011; HNUDC; MNUDC; MNUDC protein; NPD011; nuclear distribution C homolog; nuclear distribution C, dynein complex regulator; nuclear distribution gene C homolog; nuclear distribution gene C homolog (Aspergillus); nuclear distribution protein C homolog; Nuclear migration protein nudC; Nudc; nudC nuclear distribution protein; OTTHUMP00000004405; SIG-92; Silg92; silica-induced gene 92 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10726, 18221
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O35685, Q9Y266
Gene Symbols:
NUDC
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 260 of Human NUDC
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RNaseH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNASEH1
Gene Alias: H1RNA; LOC613354 protein; PEOB2; Ribonuclease H type II; ribonuclease H1; RNase H1; RNASEH1; RNH1; zgc:91971
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 246243, 436932
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.3 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: O60930
Gene Symbols: RNASEH1
Immunogen: Recombinant fragment corresponding to a region within amino acids 88 and 286 of Human RNase H1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
RNaseH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNASEH1
Gene Alias:
H1RNA; LOC613354 protein; PEOB2; Ribonuclease H type II; ribonuclease H1; RNase H1; RNASEH1; RNH1; zgc:91971
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
246243, 436932
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.3 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
O60930
Gene Symbols:
RNASEH1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 88 and 286 of Human RNase H1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: MRRF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mrrf
Gene Alias: 2400002D02Rik; mitochondrial ribosome recycling factor; MRFF; MRRF; MTRRF; Ribosome-recycling factor, mitochondrial; ribosome-releasing factor, mitochondrial; RRF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311903, 92399
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q5RKI9, Q96E11
Gene Symbols: Mrrf
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 202 of Human MRRF
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MRRF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mrrf
Gene Alias:
2400002D02Rik; mitochondrial ribosome recycling factor; MRFF; MRRF; MTRRF; Ribosome-recycling factor, mitochondrial; ribosome-releasing factor, mitochondrial; RRF
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311903, 92399
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q5RKI9, Q96E11
Gene Symbols:
Mrrf
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 202 of Human MRRF
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG