PIPA531114
UFD1L Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531114-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA531114 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
UFD1L
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UFD1
Gene Alias
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7353
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.66 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q92890
Gene Symbols
UFD1
Immunogen
Recombinant fragment corresponding to a region within amino acids 45 and 307 of Human UFD1L
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: A431
- Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (84%), Xenopus laevis (88%), Chicken (92%), Rhesus Monkey (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, which then potentiates the proteolytic degradation of these protein conjugates by the 26S proteasome
- Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or alternatively by the Ub-fusion degradation (UFD) pathway
- The UBP pathway targets the C-terminal glycine residue on Ub that is involved in the formation of Ub-conjugates, while UFD proteins preferentially cleave Ub-conjugated proteins that contain an amino acid substitution at this glycine residue
- The UFD1 protein was originally characterized in the yeast S
- cerevisiae and subsequently, the human homolog UFD1 or UFD1L was identified
- In vitro, UFD1 attenuates the degradation of Ub-fusions, which have a proline or valine residue substituted at the Gly76 moiety, by the selective multiubiquitination of the Ub chain of the Ub-conjugate
- Mutations within the UFD1 gene are implicated in the development of CATCH22 syndrome, which is characterized by cardiac defects, cleft palate and hypocalcemia, suggesting that this proteolytic pathway may be involved in the progression of these developmental defects.
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Antigen: UFD1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7353
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.66 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q92890
Gene Symbols: UFD1
Immunogen: Recombinant fragment corresponding to a region within amino acids 45 and 307 of Human UFD1L
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
UFD1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7353
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.66 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q92890
Gene Symbols:
UFD1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 45 and 307 of Human UFD1L
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ENC-2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KLHL25
Gene Alias: 2810402K13Rik; BC027373; BTB/POZ KELCH domain protein; ectodermal-neural cortex 2; ectoderm-neural cortex protein 2; ectoderm-neural cortex-1; Enc-1; ENC2; ENC-2; FLJ12587; FLJ45015; kelch like family member 25; kelch-like 25; kelch-like family member 25; kelch-like protein 25; KLHL25; RGD1310815
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 207952, 293023, 64410
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.69 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q4KLM4, Q8R2P1, Q9H0H3
Gene Symbols: KLHL25
Immunogen: Recombinant fragment corresponding to a region within amino acids 360 and 589 of Human KLHL25
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ENC-2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KLHL25
Gene Alias:
2810402K13Rik; BC027373; BTB/POZ KELCH domain protein; ectodermal-neural cortex 2; ectoderm-neural cortex protein 2; ectoderm-neural cortex-1; Enc-1; ENC2; ENC-2; FLJ12587; FLJ45015; kelch like family member 25; kelch-like 25; kelch-like family member 25; kelch-like protein 25; KLHL25; RGD1310815
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
207952, 293023, 64410
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.69 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q4KLM4, Q8R2P1, Q9H0H3
Gene Symbols:
KLHL25
Immunogen:
Recombinant fragment corresponding to a region within amino acids 360 and 589 of Human KLHL25
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDE7A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDE7A
Gene Alias: AU015378; AW047537; HCP1; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; P2A; PDE7; PDE7-1; Pde7a; phosphodiesterase 7A; phosphodiesterase isozyme 7; rolipram-insensitive phosphodiesterase type 7; TM22
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5150
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13946
Gene Symbols: PDE7A
Immunogen: Recombinant fragment corresponding to a region within amino acids 189 and 444 of Human PDE7A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PDE7A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDE7A
Gene Alias:
AU015378; AW047537; HCP1; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; P2A; PDE7; PDE7-1; Pde7a; phosphodiesterase 7A; phosphodiesterase isozyme 7; rolipram-insensitive phosphodiesterase type 7; TM22
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5150
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13946
Gene Symbols:
PDE7A
Immunogen:
Recombinant fragment corresponding to a region within amino acids 189 and 444 of Human PDE7A
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EXOSC8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXOSC8
Gene Alias: 2310032N20Rik; bA421P11.3; CBP-interacting protein 3; CIP3; EAP2; EXOSC8; Exosome complex component RRP43; exosome complex exonuclease RRP43; exosome component 8; mKIAA4013; OIP2; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; PCH1C; Ribosomal RNA-processing protein 43; RP11-421P11.3; RRP43; Rrp43p
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11340
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.42 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q96B26
Gene Symbols: EXOSC8
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 261 of Human EXOSC8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EXOSC8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXOSC8
Gene Alias:
2310032N20Rik; bA421P11.3; CBP-interacting protein 3; CIP3; EAP2; EXOSC8; Exosome complex component RRP43; exosome complex exonuclease RRP43; exosome component 8; mKIAA4013; OIP2; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; PCH1C; Ribosomal RNA-processing protein 43; RP11-421P11.3; RRP43; Rrp43p
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11340
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.42 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q96B26
Gene Symbols:
EXOSC8
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 261 of Human EXOSC8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG