PIPA531119
RNF168 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531119-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA531119 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
RNF168
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RNF168
Gene Alias
3110001H15Rik; E3 ubiquitin-protein ligase RNF168; FLJ35794; hRNF168; RING finger protein 168; ring finger protein 168, E3 ubiquitin protein ligase; ring fnger protein 168; RING-type E3 ubiquitin transferase RNF168; RNF168
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
165918
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q8IYW5
Gene Symbols
RNF168
Immunogen
Recombinant fragment corresponding to a region within amino acids 51 and 316 of Human RNF168
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: PC-3, human RNF168-transfected 293T
- Predicted reactivity: Chimpanzee (98%), Bovine (84%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- RNF168 was identified as a chromatin-associated RING finger protein that acts as a ubiquitin ligase both in vitro and in vivo
- RNF168 targets histones H2A and H2AX, but not H2B, forming K63 polyubiquitin chains
- Upon formation of DNA double strand breaks, RNF168 is recruited to the site of DNA damage where it co-localizes with -gammaH2AX and 53BP1 in an RNF8-dependent manner
- This localization of RNF168 increases the local concentration of ubiquinated proteins to the threshold required for retention of the proteins 53BP1 and BRCA1, facilitating the downstream signaling cascade
- Thus, RNF168 defines a new pathway demonstrating a functional cooperation between E3 ligases in genome maintenance
- At least three isoforms of RNF168 are known to exist.
Compare Similar Items
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Antigen: RNF168
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNF168
Gene Alias: 3110001H15Rik; E3 ubiquitin-protein ligase RNF168; FLJ35794; hRNF168; RING finger protein 168; ring finger protein 168, E3 ubiquitin protein ligase; ring fnger protein 168; RING-type E3 ubiquitin transferase RNF168; RNF168
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 165918
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q8IYW5
Gene Symbols: RNF168
Immunogen: Recombinant fragment corresponding to a region within amino acids 51 and 316 of Human RNF168
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RNF168
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNF168
Gene Alias:
3110001H15Rik; E3 ubiquitin-protein ligase RNF168; FLJ35794; hRNF168; RING finger protein 168; ring finger protein 168, E3 ubiquitin protein ligase; ring fnger protein 168; RING-type E3 ubiquitin transferase RNF168; RNF168
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
165918
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q8IYW5
Gene Symbols:
RNF168
Immunogen:
Recombinant fragment corresponding to a region within amino acids 51 and 316 of Human RNF168
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NDE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NDE1
Gene Alias: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; LIS4; MHAC; mNudE; NDE; NDE1; nuclear distribution gene E homolog 1; nuclear distribution gene E homolog 1 (A nidulans); nuclear distribution protein nudE homolog 1; NudE; nudE neurodevelopment protein 1; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; Nude1; rNudE
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54820
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NXR1
Gene Symbols: NDE1
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 203 of Human NDE1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NDE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NDE1
Gene Alias:
2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; LIS4; MHAC; mNudE; NDE; NDE1; nuclear distribution gene E homolog 1; nuclear distribution gene E homolog 1 (A nidulans); nuclear distribution protein nudE homolog 1; NudE; nudE neurodevelopment protein 1; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; Nude1; rNudE
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54820
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NXR1
Gene Symbols:
NDE1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 203 of Human NDE1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: UBE2E3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UBE2E3
Gene Alias: E2 ubiquitin-conjugating enzyme E3; Ubce4; UBCH9; UbcM2; UBE2E3; Ubiquitin carrier protein E3; ubiquitin conjugating enzyme E2 E3; ubiquitin conjugating enzyme E2E 3; ubiquitin-conjugating enzyme 4; ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3; ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog; ubiquitin-protein ligase E3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10477, 22193
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.63 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P52483, Q969T4
Gene Symbols: UBE2E3
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 207 of Human UBE2E3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
UBE2E3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UBE2E3
Gene Alias:
E2 ubiquitin-conjugating enzyme E3; Ubce4; UBCH9; UbcM2; UBE2E3; Ubiquitin carrier protein E3; ubiquitin conjugating enzyme E2 E3; ubiquitin conjugating enzyme E2E 3; ubiquitin-conjugating enzyme 4; ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3; ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog; ubiquitin-protein ligase E3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10477, 22193
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P52483, Q969T4
Gene Symbols:
UBE2E3
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 207 of Human UBE2E3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PCDHB16
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PCDHB16
Gene Alias: cadherin ME1; KIAA1621; ME1; PCDH3X; PCDHB16; PCDHB8a; PCDHbeta 16; PCDH-BETA16; PCDH-beta-16; protocadherin beta 16; protocadherin beta 8a; protocadherin beta-16; Protocadherin-3X
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57717
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NRJ7
Gene Symbols: PCDHB16
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 286 of Human PCDHB16
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PCDHB16
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PCDHB16
Gene Alias:
cadherin ME1; KIAA1621; ME1; PCDH3X; PCDHB16; PCDHB8a; PCDHbeta 16; PCDH-BETA16; PCDH-beta-16; protocadherin beta 16; protocadherin beta 8a; protocadherin beta-16; Protocadherin-3X
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57717
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NRJ7
Gene Symbols:
PCDHB16
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 286 of Human PCDHB16
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG