PIPA531172

Cyclophilin B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA531172-Each-of-1 In Stock ₹ 44,448.42

PIPA531172 - Each of 1

₹ 44,448.42

In Stock

Quantity

1

Base Price: ₹ 44,448.42

GST (18%): ₹ 8,000.716

Total Price: ₹ 52,449.136

Antigen

Cyclophilin B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PPIB

Gene Alias

AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5479

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P23284

Gene Symbols

PPIB

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 216 of Human Cyclophilin B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, HepG2
  • Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (86%), Xenopus laevis (87%), Cat (97%), Chicken (92%), Rhesus Monkey (100%), Bovine (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation
  • Thus, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.

Compare Similar Items

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Img

Thermo Scientific

PIPA531172

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Antigen:
Cyclophilin B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPIB

Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5479

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P23284

Gene Symbols:
PPIB

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 216 of Human Cyclophilin B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA531173

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Antigen:
PSME1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSME1

Gene Alias:
11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5720

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q06323

Gene Symbols:
PSME1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 218 of Human PSME1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA531175

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Antigen:
CAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXADR

Gene Alias:
2610206D03Rik; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; AU016810; AW553441; CAR; Car1; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; coxsackievirus B-adenovirus receptor; CVB3-binding protein; Cxadr; HCAR; HCVADR; MCAR; MCVADR; rCAR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1525, 89843

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.05 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P78310, Q9R066

Gene Symbols:
CXADR

Immunogen:
Recombinant fragment corresponding to a region within amino acids 36 and 358 of Human CAR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA531176

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Antigen:
GNA15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNA15

Gene Alias:
Epididymis tissue protein Li 17E; G alpha 15; G alpha 16; g alpha-15; G alpha-16; G protein subunit alpha 15; G[a]15; Galpha15; GNA 15; GNA 16; GNA15; Gna-15; GNA16; G-protein subunit alpha-15; G-protein subunit alpha-16; Gq class; guanine nucleotide binding protein (G protein), alpha 15 (Gq class); guanine nucleotide binding protein, alpha 15; guanine nucleotide-binding protein subunit alpha-15; Guanine nucleotide-binding protein subunit alpha-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2769

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P30679

Gene Symbols:
GNA15

Immunogen:
Recombinant fragment corresponding to a region within amino acids 112 and 374 of Human G protein alpha 16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG