PIPA531319
PHLPP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531319-Each-of-1 | In Stock | ₹ 44,619.54 |
PIPA531319 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
PHLPP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Phlpp2
Gene Alias
AI481772; C130044A18Rik; GTPase activating protein and VPS9 domains 1; KIAA0931; PH domain and leucine rich repeat protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP2; Phlppl; PHLPP-like; PPM3B; protein phosphatase, Mg2+/Mn2+ dependent 3B; RGD1562857
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23035, 244650
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q6ZVD8, Q8BXA7
Gene Symbols
Phlpp2
Immunogen
Recombinant fragment corresponding to a region within amino acids 13 and 234 of Human PHLPP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: mouse brain
- Predicted reactivity: Mouse (96%), Rat (97%), Bovine (95%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Protein phosphatase involved in regulation of Akt and PKC signaling
- Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA
- Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes
- Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and decreases cell proliferation
- Also controls the phosphorylation of AKT3
- Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis (PubMed:20513427)
- Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation (PubMed:21986499)
- Inhibits cancer cell proliferation and may act as a tumor suppressor
- Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation
- Dephosphorylates RAF1 inhibiting its kinase activity (PubMed:24530606)
- [UniProt]
Compare Similar Items
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Antigen: PHLPP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Phlpp2
Gene Alias: AI481772; C130044A18Rik; GTPase activating protein and VPS9 domains 1; KIAA0931; PH domain and leucine rich repeat protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP2; Phlppl; PHLPP-like; PPM3B; protein phosphatase, Mg2+/Mn2+ dependent 3B; RGD1562857
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23035, 244650
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q6ZVD8, Q8BXA7
Gene Symbols: Phlpp2
Immunogen: Recombinant fragment corresponding to a region within amino acids 13 and 234 of Human PHLPP2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PHLPP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Phlpp2
Gene Alias:
AI481772; C130044A18Rik; GTPase activating protein and VPS9 domains 1; KIAA0931; PH domain and leucine rich repeat protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP2; Phlppl; PHLPP-like; PPM3B; protein phosphatase, Mg2+/Mn2+ dependent 3B; RGD1562857
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23035, 244650
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q6ZVD8, Q8BXA7
Gene Symbols:
Phlpp2
Immunogen:
Recombinant fragment corresponding to a region within amino acids 13 and 234 of Human PHLPP2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: YARS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: YARS2
Gene Alias: 2210023C10Rik; CGI-04; EC 6.1.1.1; fi41d10; LOC556702 protein; LOW QUALITY PROTEIN: tyrosine--tRNA ligase, mitochondrial; MLASA2; MT-TYRRS; RGD1311696; tyrosine tRNA ligase 2, mitochondrial; tyrosine--tRNA ligase, mitochondrial; tyrosyl trna synthetase; Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 2; tyrosyl-tRNA synthetase 2 (mitochondrial); tyrosyl-tRNA synthetase 2, mitochondrial; tyrosyl-tRNA synthetase mitochondrial-like protein; tyrosyl-tRNA synthetase, mitochondrial; tyrRS; wu:fi41d10; Yars2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51067
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.79 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9Y2Z4
Gene Symbols: YARS2
Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 227 of Human YARS2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
YARS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
YARS2
Gene Alias:
2210023C10Rik; CGI-04; EC 6.1.1.1; fi41d10; LOC556702 protein; LOW QUALITY PROTEIN: tyrosine--tRNA ligase, mitochondrial; MLASA2; MT-TYRRS; RGD1311696; tyrosine tRNA ligase 2, mitochondrial; tyrosine--tRNA ligase, mitochondrial; tyrosyl trna synthetase; Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 2; tyrosyl-tRNA synthetase 2 (mitochondrial); tyrosyl-tRNA synthetase 2, mitochondrial; tyrosyl-tRNA synthetase mitochondrial-like protein; tyrosyl-tRNA synthetase, mitochondrial; tyrRS; wu:fi41d10; Yars2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51067
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.79 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9Y2Z4
Gene Symbols:
YARS2
Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 227 of Human YARS2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MRPS23
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MRPS23
Gene Alias: 28S ribosomal protein S23, mitochondrial; CGI-138; D11Bwg1153e; HSPC329; mitochondrial ribosomal protein S23; Mitochondrial small ribosomal subunit protein mS23; MRPS23; MRP-S23; Rpms23; S23mt
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51649
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9Y3D9
Gene Symbols: MRPS23
Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 164 of Human MRPS23
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MRPS23
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MRPS23
Gene Alias:
28S ribosomal protein S23, mitochondrial; CGI-138; D11Bwg1153e; HSPC329; mitochondrial ribosomal protein S23; Mitochondrial small ribosomal subunit protein mS23; MRPS23; MRP-S23; Rpms23; S23mt
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51649
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9Y3D9
Gene Symbols:
MRPS23
Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 164 of Human MRPS23
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: WDR74
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WDR74
Gene Alias: 5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54663
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q6RFH5
Gene Symbols: WDR74
Immunogen: Recombinant fragment corresponding to a region within amino acids 50 and 266 of Human WDR74
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
WDR74
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WDR74
Gene Alias:
5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54663
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q6RFH5
Gene Symbols:
WDR74
Immunogen:
Recombinant fragment corresponding to a region within amino acids 50 and 266 of Human WDR74
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG