PIPA531809

UBXN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA531809-Each-of-1 In Stock ₹ 47,015.22

PIPA531809 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

UBXN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBXN1

Gene Alias

2B28; 4930455J02Rik; D19Ertd721e; mY33K; Protein 2B28; RGD1309471; SAKS1; SAPK substrate protein 1; T25529; UBA/UBX 33.3 kDa protein; UBX domain protein 1; UBX domain-containing protein 1; UBXD10; UBXN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

225896, 51035

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.78 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q04323, Q922Y1

Gene Symbols

UBXN1

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 106 and 297 of Human UBXN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, HeLa, NIH-3T3, JC, BCL-1
  • Predicted reactivity: Mouse (91%), Rat (87%), Bovine (93%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Ubiquitin-binding protein that plays a role in the modulation of innate immune response
  • Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways
  • Following viral infection, UBXN1 is induced and recruited to the RLR component MAVS
  • In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome
  • This function probably serves as a brake to prevent excessive RLR signaling (PubMed:23545497)
  • Interferes with the TNFalpha-triggered NF-kappa-B pathway by interacting with cellular inhibitors of apoptosis proteins (cIAPs) and thereby inhibiting their recruitment to TNFR1 (PubMed:25681446)
  • Prevents also the activation of NF-kappa-B by associating with CUL1 and thus inhibiting NF-kappa-B inhibitor alpha/NFKBIA degradation that remains bound to NF-kappa-B (PubMed:28152074)
  • Interacts with the BRCA1-BARD1 heterodimer and regulates its activity
  • Specifically binds 'Lys-6'-linked polyubiquitin chains
  • Interaction with autoubiquitinated BRCA1 leads to the inhibition of the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer (PubMed:20351172)
  • Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol
  • [UniProt]

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Show Difference

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PIPA531809

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Antigen:
UBXN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBXN1

Gene Alias:
2B28; 4930455J02Rik; D19Ertd721e; mY33K; Protein 2B28; RGD1309471; SAKS1; SAPK substrate protein 1; T25529; UBA/UBX 33.3 kDa protein; UBX domain protein 1; UBX domain-containing protein 1; UBXD10; UBXN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225896, 51035

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.78 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q04323, Q922Y1

Gene Symbols:
UBXN1

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 106 and 297 of Human UBXN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA531812

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Antigen:
WDR69

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAW1

Gene Alias:
DAW1; dynein assembly factor with WD repeats 1; dynein assembly factor with WDR repeat domains 1; ODA16; outer row dynein assembly 16 homolog; outer row dynein assembly protein 16 homolog; testis tissue sperm-binding protein Li 93mP; WD repeat domain 69; WD repeat-containing protein 69; WDR69

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
164781

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8N136

Gene Symbols:
DAW1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 231 of Human WDR69

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA531814

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Antigen:
ZC3H10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZC3H10

Gene Alias:
AI790326; hypothetical protein zgc:77248; RPL41; SI:zC239J9.3; ZC3H10; ZC3HDC10; zgc:77248; Zinc finger CCCH domain-containing protein 10; zinc finger CCCH type containing 10; zinc finger CCCH-type containing 10; zinc finger CCCH-type domain containing 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84872

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.89 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96K80

Gene Symbols:
ZC3H10

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 228 of Human ZC3H10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA531815

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Antigen:
ZNF711

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF711

Gene Alias:
2810409C01Rik; A230078I01Rik; CMPX1; dJ75N13.1; dJ75N13.1 (znf6-like); MRX97; Zfp711; Zinc finger protein 6; zinc finger protein 6 (CMPX1); zinc finger protein 711; ZNF4; ZNF5; ZNF6; ZNF711

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7552

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9Y462

Gene Symbols:
ZNF711

Immunogen:
Recombinant fragment corresponding to a region within amino acids 126 and 361 of Human ZNF711

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG