PIPA532420

GLC1D Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532420-Each-of-1 In Stock ₹ 42,694.44

PIPA532420 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

GLC1D

Classification

Polyclonal

Gene

GLC1D

Gene Symbols

GLC1D

Immunogen

Synthetic peptide derived from internal region of heavy subunit of GCS protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene Alias

GLCLR, GCS light chain, GSC light chain, gamma-ECS regulatory subunit, gamma-glutamylcysteine synthetase regulatory subunit, glutamate--cysteine ligase modifier subunit, glutamate--cysteine ligase regulatory subunit, glutamate-cysteine ligase gamma-glutamylcysteine s

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2724

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
  • A suggested positive control is kidney or testis tissue
  • Gamma Glutamylcystuene Synthetase (GSH) is the first enzyme and rate limiting step in the slutathione biosynthesis pathway
  • Glutathione (GSH) plays an important role in detoxification of oxidants and toxins from the cells
  • In most cells, GSH is synthesized denovo in two steps catalysed by Gamma Glutamylcysteine Synthetase (GCS) / Glutamate-cystein Ligase and GSH homeostasis
  • It is composed of two subunits: heavy and light
  • These subunits are coded by different genes which are controlled by different mechanisms
  • The heavy subunit carries the catalytic activity and can be inhibited through feedback mechanism by GSH
  • Binding of light subunit to heavy subunit reduces the Michaelis-Menten constant for glutamate to a physiological concentration of 1.2mM and increases the inhibitory constant for GSH.

Compare Similar Items

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Thermo Scientific

PIPA532420

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Antigen:
GLC1D

Classification:
Polyclonal

Gene:
GLC1D

Gene Symbols:
GLC1D

Immunogen:
Synthetic peptide derived from internal region of heavy subunit of GCS protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene Alias:
GLCLR, GCS light chain, GSC light chain, gamma-ECS regulatory subunit, gamma-glutamylcysteine synthetase regulatory subunit, glutamate--cysteine ligase modifier subunit, glutamate--cysteine ligase regulatory subunit, glutamate-cysteine ligase gamma-glutamylcysteine s

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2724

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA532425

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Antigen:
GluR1

Classification:
Polyclonal

Gene:
GRIA1

Gene Symbols:
GRIA1

Immunogen:
Synthetic peptide from C-terminus of human GluR1.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene Alias:
2900051M01Rik; AI853806; AMPA 1; AMPA glutamate receptor; AMPA receptor GluR1/A; AMPA-selective glutamate receptor 1; Glr1; Glr-1; GluA1; GLUH 1; GLUH1; GluR K1; GLUR1; Glur-1; GluR1 flip; GluR1 flop; GLURA; GluR-A; GluRK1; gluR-K1; glutamate ionotropic receptor AMPA type subunit 1; glutamate receptor; glutamate receptor 1; glutamate receptor A; glutamate receptor ionotropic, AMPA 1; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA1 (alpha 1); GPRC1A; Gria 1; Gria1; GRM1A; HBGR1; HGBR1; HIPA; HIPA1; MGC13325; MGC133252; NMDA1; NMDAR1; NR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243; RP11-350O14.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2890

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA532434

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Antigen:
Granzyme B

Classification:
Polyclonal

Gene:
GZMB

Gene Symbols:
GZMB

Immunogen:
Synthetic peptide from N-terminus of human granzyme B.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3002

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA532437

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Antigen:
GRP78

Classification:
Polyclonal

Gene:
Hspa5

Gene Symbols:
Hspa5

Immunogen:
Synthetic peptide corresponding to near N-terminus of human GRP78

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene Alias:
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14828, 3309, 396487

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid