PIPA532450

ID3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532450-Each-of-1 In Stock ₹ 42,181.08

PIPA532450 - Each of 1

₹ 42,181.08

In Stock

Quantity

1

Base Price: ₹ 42,181.08

GST (18%): ₹ 7,592.594

Total Price: ₹ 49,773.674

Antigen

ID3

Classification

Polyclonal

Gene

ID3

Gene Alias

HEIR-1, bHLHb25, DNA-binding protein inhibitor ID-3, ID-like protein inhibitor HLH 1R21, class B basic helix-loop-helix protein 25, helix-loop-helix protein HEIR-1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15903, 3399

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Gene Accession No.

P41133, Q02535

Gene Symbols

ID3

Immunogen

Synthetic peptide corresponding to C-terminus of human ID-3

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
  • A suggested positive control is breast carcinoma
  • Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3 and ID4
  • They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins
  • Due to the absence of the basic region, the resulting heterodimers cannot bind DNA
  • The ID-type proteins thus appear to negatively regulate DNA binding of bHLH proteins
  • Since ID1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression
  • Under conditions that facilitate muscle cell differentiation, the ID protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation
  • It has been shown that expression of each of the ID proteins is strongly dependent on growth factor activation and that reduction of ID mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA532450

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Antigen:
ID3

Classification:
Polyclonal

Gene:
ID3

Gene Alias:
HEIR-1, bHLHb25, DNA-binding protein inhibitor ID-3, ID-like protein inhibitor HLH 1R21, class B basic helix-loop-helix protein 25, helix-loop-helix protein HEIR-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15903, 3399

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene Accession No.:
P41133, Q02535

Gene Symbols:
ID3

Immunogen:
Synthetic peptide corresponding to C-terminus of human ID-3

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA532454

--


Antigen:
Involucrin

Classification:
Polyclonal

Gene:
IVL

Gene Alias:
1110019C06Rik; involucrin; IVL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3713

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
P07476

Gene Symbols:
IVL

Immunogen:
Recombinant protein encoding aa 420-578 of human involucrin.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA532463

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Antigen:
Cytokeratin 19

Classification:
Polyclonal

Gene:
KRT19

Gene Alias:
40-kDa keratin intermediate filament; AI663979; C K1CS; CK 19; CK19; CK-19; cytokeratin 19; cytokeratin-19; EndoC; K19; K1CS; Ka19; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Krt-1.19; Krt1-19; Krt19; LOC100344434; MGC15366; Type I keratin Ka19

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3880

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
P08727

Gene Symbols:
KRT19

Immunogen:
Synthetic peptide derived from C-terminus of human Keratin 19

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA532464

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Antigen:
Cytokeratin 20

Classification:
Polyclonal

Gene:
KRT20

Gene Alias:
9030623C06Rik; CD20; CK20; CK-20; CK-21; cytokeratin 20; cytokeratin 21; cytokeratin-20; Cytokeratin-21; K20; keratin 20; keratin 20, type I; keratin, type I cytoskeletal 20; Keratin-20; krt20; Krt21; MGC35423; Protein IT

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54474

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
P35900

Gene Symbols:
KRT20

Immunogen:
Synthetic peptide corresponding to C-terminus of human keratin 20

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG