PIPA532979

PDE8A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA532979-Each-of-1 In Stock ₹ 44,705.10

PIPA532979 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PDE8A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pde8a

Gene Alias

AI551852; cAMP-specific cyclic nucleotide phosphodiesterase 8A; cAMP-specific cyclic nucleotide phosphodiesterase PDE8; FLJ16150; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A; HsT19550; mmPDE8; Pde8; PDE8A; phosphodiesterase 8A; RNPDE8A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100068475, 100343099, 488752, 5151

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

O60658

Gene Symbols

Pde8a

Immunogen

Synthetic 16 amino acid peptide from near N-terminus of human PDE8A.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Canine, Equine, Human, Rabbit

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Panda, Horse, Rabbit, Pig (100%); Marmoset (94%); Mouse, Rat, Bovine, Elephant, Opossum (88%); Platypus, Zebrafish (81%)
  • For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
  • After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
  • Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP
  • These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction
  • PDEs comprise a large superfamily of enzymes divided into 10 families
  • Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors
  • Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., 2000).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA532979

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Antigen:
PDE8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pde8a

Gene Alias:
AI551852; cAMP-specific cyclic nucleotide phosphodiesterase 8A; cAMP-specific cyclic nucleotide phosphodiesterase PDE8; FLJ16150; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A; HsT19550; mmPDE8; Pde8; PDE8A; phosphodiesterase 8A; RNPDE8A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100068475, 100343099, 488752, 5151

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O60658

Gene Symbols:
Pde8a

Immunogen:
Synthetic 16 amino acid peptide from near N-terminus of human PDE8A.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Canine, Equine, Human, Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA532981

--


Antigen:
PDE8B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDE8B

Gene Alias:
3',5' cyclic nucleotide phosphodiesterase 8B; ADSD; B230331L10Rik; C030047E14Rik; cAMP-specific cyclic nucleotide phosphodiesterase PDE8; cell proliferation-inducing gene 22 protein; FLJ11212; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; hsPDE8B; Pde8b; phosphodiesterase 8B; PIG22; PPNAD3; RNPDE8B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8622

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.3 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O95263

Gene Symbols:
PDE8B

Immunogen:
Synthetic 16 amino acid peptide from internal region of human PDE8B.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA532983

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Antigen:
PDGFRB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdgfrb

Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5159

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P09619

Gene Symbols:
Pdgfrb

Immunogen:
Synthetic 16 amino acid peptide from extracellular domain of human PDGFRB.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA532987

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Antigen:
PLA2G3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLA2G3

Gene Alias:
giii; GIII sPLA2; GIII-SPLA2; Group 3 secretory phospholipase A2; group III secreted phospholipase A2; Group III secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2 group III; phospholipase A2, group III; PLA2G3; SPLA2III; sPLA2-III

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50487

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q9NZ20

Gene Symbols:
PLA2G3

Immunogen:
Synthetic 16 amino acid peptide from internal region of human PLA2G3.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG