PIPA533903

LPHN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533903-Each-of-1 In Stock ₹ 44,705.10

PIPA533903 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

LPHN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Adgrl1

Gene Alias

2900070I05Rik; ADGRL1; Adhesion G protein-coupled receptor L1; AI182398; calcium-independent alpha-latrotoxin receptor 1; Cirl; Cirl1; CIRL-1; CL1; CL1BA; CLIBA; KIAA0821; latrophilin 1; latrophilin-1; LEC2; Lectomedin-2; Lphh2; LPHN1; mKIAA0821

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100359196, 100514215, 100760780, 22859, 330814, 65096, 788252

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.74 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

O88917, O94910, O97831, Q80TR1

Gene Symbols

Adgrl1

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN1.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Adgrl1 (Latrophilin-1) is a calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells
  • Adgrl1 is a receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization, and may be implicated in the regulation of exocytosis
  • The Adgrl1 gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR)
  • Latrophilins may function in both cell adhesion and signal transduction
  • In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane
  • Adgrl1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane
  • Alternative splicing results in multiple variants encoding distinct isoforms of Adgrl1
  • Diseases associated with ADGRL1 include Dermatophytosis and Retinal Degeneration, Late-Onset, Autosomal Dominant.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA533903

--


Antigen:
LPHN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adgrl1

Gene Alias:
2900070I05Rik; ADGRL1; Adhesion G protein-coupled receptor L1; AI182398; calcium-independent alpha-latrotoxin receptor 1; Cirl; Cirl1; CIRL-1; CL1; CL1BA; CLIBA; KIAA0821; latrophilin 1; latrophilin-1; LEC2; Lectomedin-2; Lphh2; LPHN1; mKIAA0821

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359196, 100514215, 100760780, 22859, 330814, 65096, 788252

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.74 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O88917, O94910, O97831, Q80TR1

Gene Symbols:
Adgrl1

Immunogen:
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533905

--


Antigen:
LPHN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADGRL2

Gene Alias:
Adgrl2; Adhesion G protein-coupled receptor L2; AI450192; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; Cirl2; Cirl-2; Cl2; Cl2aa; Cl2ac; Gm619; KIAA0786; latrophilin 1; latrophilin 2; latrophilin homolog 1; Latrophilin-2; LEC1; Lectomedin-1; LPHH1; Lphn2; mKIAA0786

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O95490

Gene Symbols:
ADGRL2

Immunogen:
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533907

--


Antigen:
LPHN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADGRL2

Gene Alias:
Adgrl2; Adhesion G protein-coupled receptor L2; AI450192; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; Cirl2; Cirl-2; Cl2; Cl2aa; Cl2ac; Gm619; KIAA0786; latrophilin 1; latrophilin 2; latrophilin homolog 1; Latrophilin-2; LEC1; Lectomedin-1; LPHH1; Lphn2; mKIAA0786

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O95490

Gene Symbols:
ADGRL2

Immunogen:
Synthetic 16 amino acid peptide from C-terminus of human LPHN2.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533908

--


Antigen:
LPHN3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADGRL3

Gene Alias:
5430402I23Rik; ADGRL3; Adhesion G protein-coupled receptor L3; calcium-independent alpha-latrotoxin receptor 3; calcium-independent alpha-latrotoxin receptor homolog 3; Cirl3; CIRL-3; Cl3; D130075K09Rik; Gm1379; Kiaa0768; latrophilin 3; latrophilin homolog 3 (cow); latrophilin-3; LEC3; lectomedin 3; lectomedin-3; Lph3; LPHN3; mKIAA0768

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100056929, 100338255, 170641, 23284, 422616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q9HAR2, Q9Z173

Gene Symbols:
ADGRL3

Immunogen:
Synthetic 19 amino acid peptide from C-terminus of human LPHN3.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Equine, Human, Non-human Primate, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG