PIPA533914

TPL2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533914-Each-of-1 In Stock ₹ 44,790.66

PIPA533914 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

TPL2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K8

Gene Alias

augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1326, 487085, 535622

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P41279

Gene Symbols

MAP3K8

Immunogen

Synthetic 18 amino acid peptide from near C-terminus of human MAP3K8.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Bovine, Dog, Bat (100%) Mouse, Rat, Hamster, Panda, Horse (94%)
  • MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
  • Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
  • MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
  • The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
  • MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
  • This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
  • The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
  • The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA533914

--


Antigen:
TPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1326, 487085, 535622

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P41279

Gene Symbols:
MAP3K8

Immunogen:
Synthetic 18 amino acid peptide from near C-terminus of human MAP3K8.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533916

--


Antigen:
MLK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K9

Gene Alias:
E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100054289, 100341731, 338372, 4293

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P80192, Q3U1V8

Gene Symbols:
MAP3K9

Immunogen:
Synthetic 18 amino acid peptide from internal region of human MAP3K9.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Equine, Human, Mouse, Non-human Primate, Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA533918

--


Antigen:
MAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAS1

Gene Alias:
angiotensin-(1-7) receptor; c-mas; MAS; MAS proto-oncogene; MAS1; Mas-1; MAS1 oncogene; Mas1 proto-oncogene; MAS1 proto-oncogene, G protein-coupled receptor; Mas-related G protein-coupled receptor a; MGC119966; MGRA; Proto-oncogene Mas

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100522470, 17171, 4142, 783010

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P04201, P30554

Gene Symbols:
MAS1

Immunogen:
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MAS1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Hamster, Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533919

--


Antigen:
MAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAS1

Gene Alias:
angiotensin-(1-7) receptor; c-mas; MAS; MAS proto-oncogene; MAS1; Mas-1; MAS1 oncogene; Mas1 proto-oncogene; MAS1 proto-oncogene, G protein-coupled receptor; Mas-related G protein-coupled receptor a; MGC119966; MGRA; Proto-oncogene Mas

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4142

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P04201

Gene Symbols:
MAS1

Immunogen:
Synthetic 17 amino acid peptide from 2nd extracellular domain of human MAS1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG