PIPA534283

TRPM4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534283-Each-of-1 In Stock ₹ 44,705.10

PIPA534283 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TRPM4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRPM4

Gene Alias

1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54795

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

Q8TD43

Gene Symbols

TRPM4

Immunogen

Synthetic 17 amino acid peptide from N-Terminus of human TRPM4.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human (100%); Chimpanzee, Gorilla, Orangutan, Monkey, Mouse (94%); Gibbon, Galago, Rat, Dog (88%); Marmoset, Elephant, Panda, Bovine, Pig (82%)
  • Use in IHC with formalin-fixed paraffin-embedded tissues requires proteinase K digestion for antigen retrieval
  • Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization
  • While it is activated by increase in intracellular Ca2+, it is impermeable to it
  • Mediates transport of monovalent cations (Na+, K+, Cs+, Li+), leading to depolarize the membrane
  • It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc
  • Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production
  • Involved in myogenic constriction of cerebral arteries
  • Controls insulin secretion in pancreatic beta-cells
  • May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload
  • Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization
  • Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA534283

--


Antigen:
TRPM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPM4

Gene Alias:
1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54795

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q8TD43

Gene Symbols:
TRPM4

Immunogen:
Synthetic 17 amino acid peptide from N-Terminus of human TRPM4.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534284

--


Antigen:
TRPM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPM4

Gene Alias:
1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100295930, 54795, 68667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q7TN37, Q8TD43

Gene Symbols:
TRPM4

Immunogen:
Synthetic 16 amino acid peptide from internal region of human TRPM4.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA534288

--


Antigen:
TRPV1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPV1

Gene Alias:
Capsaicin receptor; cation channel; DKFZp434K0220; non-selective cation channel; osm-9-like TRP channel 1; OTRPC1; si:dkey-9e15.2; transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel V1; transient receptor potential cation channel, subfamily V, member 1; transient receptor potential V1; transient receptor potential V1 channel; transient receptor potential vanilloid 1 supraoptic nucleus; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b; TRPV1; TRPV1/2; TRPV1_SON; TRPV1alpha; TRPV1beta; Vanilloid receptor; vanilloid receptor 1; vanilloid receptor subtype 1; vanilloid receptor type 1 like protein 1; Vanilloid receptor type 1-like; vanilloid type 1 receptor; VR.5'sv; Vr1; VR-1; Vr1l; Vr1l1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100135466, 7442

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q6R5A3, Q8NER1

Gene Symbols:
TRPV1

Immunogen:
Synthetic 17 amino acid peptide from internal region of human TRPV1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534290

--


Antigen:
TRPV2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trpv2

Gene Alias:
GRC; growth factor regulated channel; growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Sac2b; Stretch-activated channel 2B; transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; Trpv2; Vanilloid receptor-like protein 1; VRL; Vrl1; VRL-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51393

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q9Y5S1

Gene Symbols:
Trpv2

Immunogen:
Synthetic 15 amino acid peptide from internal region of human TRPV2.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG