PIPA534427

SCUBE3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534427-Each-of-1 In Stock ₹ 47,528.58

PIPA534427 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

SCUBE3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCUBE3

Gene Alias

CEGF3; CUB domain and EGF-like repeat containing 3; D030038I21Rik; SCUBE3; signal peptide; signal peptide, CUB and EGF-like domain containing protein 3; signal peptide, CUB and EGF-like domain-containing protein 3; signal peptide, CUB domain and EGF like domain containing 3; signal peptide, CUB domain, EGF-like 3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

222663, 268935

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q66PY1, Q8IX30

Gene Symbols

SCUBE3

Immunogen

A 15 amino acid synthetic peptide near the center of human SCUBE3

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is mouse kidney tissue lysate
  • PA5-34427 can be used with blocking peptide PEP-1469
  • SCUBE3 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and is highly expressed in primary osteoblasts and bones, and to a lesser extent in heart
  • Other studies have shown that overexpression of SCUBE3 in mice induced cardiac hypertrophy, suggesting that it may also play a role in the regulation of cardiac growth
  • SCUBE3 has been shown to be an endogenous TGF-Beta receptor ligand and is thought to promote lung cancer cell mobility and invasiveness
  • In lung cancer cells, the secreted SCUBE3 protein was cleaved by MMP2 and MMP9, allowing the activation of the TGF-Beta receptor, the increase of Smad2/3 transcriptional activity and the upregulation of expression of proteins such as TGF-Beta1, VEGF, Snail, and Slug.

Compare Similar Items

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Img

Thermo Scientific

PIPA534427

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Antigen:
SCUBE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCUBE3

Gene Alias:
CEGF3; CUB domain and EGF-like repeat containing 3; D030038I21Rik; SCUBE3; signal peptide; signal peptide, CUB and EGF-like domain containing protein 3; signal peptide, CUB and EGF-like domain-containing protein 3; signal peptide, CUB domain and EGF like domain containing 3; signal peptide, CUB domain, EGF-like 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
222663, 268935

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q66PY1, Q8IX30

Gene Symbols:
SCUBE3

Immunogen:
A 15 amino acid synthetic peptide near the center of human SCUBE3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534428

--


Antigen:
ATG2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATG2B

Gene Alias:
2410024A21Rik; AI047755; AI503411; ATG2 autophagy related 2 homolog B; Atg2b; autophagy related 2B; autophagy-related protein 2 homolog B; AW558123; C030004M05Rik; C14orf103; C630028L02Rik; mKIAA4067; RGD1304878

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55102

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q96BY7

Gene Symbols:
ATG2B

Immunogen:
A 19 amino acid synthetic peptide near the amino terminus of human ATG2B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534429

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Antigen:
CBX4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBX4

Gene Alias:
Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12418, 501403, 8535

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00257, O55187

Gene Symbols:
CBX4

Immunogen:
A 17 amino acid synthetic peptide near the amino terminus of human CBX4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534430

--


Antigen:
EED

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EED

Gene Alias:
EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13626, 293104, 8726

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O75530, Q921E6

Gene Symbols:
EED

Immunogen:
An 18 amino acid synthetic peptide near the amino terminus of human EED

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG