PIPA534556

RIP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534556-Each-of-1 In Stock ₹ 47,015.22

PIPA534556 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

RIP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RIPK1

Gene Alias

cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8737

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q13546

Gene Symbols

RIPK1

Immunogen

A 14 amino acid peptide near the carboxy terminus of human RIP1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA5-34556 can be used with blocking peptide PEP-1599
  • Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
  • Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
  • Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
  • Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
  • Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
  • Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
  • RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA534556

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Antigen:
RIP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8737

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q13546

Gene Symbols:
RIPK1

Immunogen:
A 14 amino acid peptide near the carboxy terminus of human RIP1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534557

--


Antigen:
RIM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rims2

Gene Alias:
2810036I15Rik; AW048769; KIAA0751; mKIAA0751; Nim2; non-small cell lung cancer RimL3a protein; non-small cell lung cancer RimL3c protein; nuclear protein; OBOE; Rab3 interacting protein 1; Rab3 interacting protein 2; RAB3 interacting protein 3; Rab-3-interacting molecule 2; rab3-interacting molecule 2; Rab3-interacting protein; rab-3-interacting protein 2; rab3-interacting protein 2; Rab-3-interacting protein 3; Rab3ip2; RAB3IP3; regulating synaptic membrane exocytosis 2; regulating synaptic membrane exocytosis protein 2; RIM 2; Rim2; RIM2 (CT); Rim2(+40A); Rim2(+44A); Rim2(+4A); Rims2; Serg2; synaptic exocytosis regulator 2; synaptotagmin 3, related sequence; Syt3-rs

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9699

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9UQ26

Gene Symbols:
Rims2

Immunogen:
A 16 amino acid peptide near the carboxy terminusof human RIM2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534558

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Antigen:
SCUBE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCUBE3

Gene Alias:
CEGF3; CUB domain and EGF-like repeat containing 3; D030038I21Rik; SCUBE3; signal peptide; signal peptide, CUB and EGF-like domain containing protein 3; signal peptide, CUB and EGF-like domain-containing protein 3; signal peptide, CUB domain and EGF like domain containing 3; signal peptide, CUB domain, EGF-like 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
222663

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8IX30

Gene Symbols:
SCUBE3

Immunogen:
A 15 amino acid peptide near the center of human SCUBE3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534561

--


Antigen:
TRIM24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM24

Gene Alias:
A130082H20Rik; Ab2-427; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; Tif1; Tif1a; TIF1alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; transcriptional intermediary factor 1, alpha; Trim24; tripartite motif containing 24; tripartite motif-containing 24; tripartite motif-containing protein 24

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21848, 500084, 8805

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O15164, Q64127

Gene Symbols:
TRIM24

Immunogen:
A 19 amino acid peptide near the center of human TRIM24

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG