PIPA534626
Chk1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA534626-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA534626 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
Chk1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1111
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O14757
Gene Symbols
Chek1
Immunogen
Synthetic peptide corresponding to a region within amino acids 259 and 351 of CHK1 (Uniprot ID#O14757)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: human Chk1-transfected 293T
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Chk1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1111
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O14757
Gene Symbols: Chek1
Immunogen: Synthetic peptide corresponding to a region within amino acids 259 and 351 of CHK1 (Uniprot ID#O14757)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Chk1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1111
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O14757
Gene Symbols:
Chek1
Immunogen:
Synthetic peptide corresponding to a region within amino acids 259 and 351 of CHK1 (Uniprot ID#O14757)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ERG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Erg
Gene Alias: avian erythroblastosis virus E-26 (v-ets) oncogene related; D030036I24Rik; ERG; ERG, ETS transcription factor; ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; Erg-3; erythroblast transformation-specific transcription factor ERG variant 10; ETS transcription factor ERG; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; p55; TMPRSS2/ERG fusion; transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); transcriptional regulator ERG; LOW QUALITY PROTEIN: transcriptional regulator ERG; Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 13876, 170909, 2078
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P11308, P81270
Gene Symbols: Erg
Immunogen: Synthetic peptide corresponding to a region within amino acids 419 and 486 of ERG (Uniprot ID#P11308)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ERG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Erg
Gene Alias:
avian erythroblastosis virus E-26 (v-ets) oncogene related; D030036I24Rik; ERG; ERG, ETS transcription factor; ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; Erg-3; erythroblast transformation-specific transcription factor ERG variant 10; ETS transcription factor ERG; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; p55; TMPRSS2/ERG fusion; transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); transcriptional regulator ERG; LOW QUALITY PROTEIN: transcriptional regulator ERG; Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13876, 170909, 2078
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P11308, P81270
Gene Symbols:
Erg
Immunogen:
Synthetic peptide corresponding to a region within amino acids 419 and 486 of ERG (Uniprot ID#P11308)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CCR8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCR8
Gene Alias: C-C; CC chemokine receptor 8; CC chemokine receptor CHEMR1; C-C chemokine receptor type 8; C-C CKR-8; C-C motif chemokine receptor 8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; cd198; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CKR-8; CKRL1; CKR-L1; Cmkbr8; CMKBRL2; CY6; GPRCY6; GPR-CY6; mCCR8; MGC129966; MGC129973; TER1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1237
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P51685
Gene Symbols: CCR8
Immunogen: Synthetic peptide corresponding to a region within amino acids 255 and 355 of CCR8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CCR8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCR8
Gene Alias:
C-C; CC chemokine receptor 8; CC chemokine receptor CHEMR1; C-C chemokine receptor type 8; C-C CKR-8; C-C motif chemokine receptor 8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; cd198; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CKR-8; CKRL1; CKR-L1; Cmkbr8; CMKBRL2; CY6; GPRCY6; GPR-CY6; mCCR8; MGC129966; MGC129973; TER1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1237
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P51685
Gene Symbols:
CCR8
Immunogen:
Synthetic peptide corresponding to a region within amino acids 255 and 355 of CCR8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Endothelin B Receptor
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EDNRB
Gene Alias: ABCDS; AU022549; Ednra; Ednrb; endothelin B receptor; endothelin receptor non-selective type; endothelin receptor subtype B1; endothelin receptor type B; endothelin-B receptor; ETb; ET-B; Etb receptor; Et-b receptor; ETB1; ETBR; ET-BR; Et-b-r; Etb-svr; ETRB; ET-RB; ETR-b; HSCR; HSCR2; piebald; RP11-318G21.1; Sox10m1; WS4A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1910
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P24530
Gene Symbols: EDNRB
Immunogen: Synthetic peptide corresponding to a region within amino acids 9 and 101 of Endothelin B Receptor (Uniprot ID#P24530)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Endothelin B Receptor
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EDNRB
Gene Alias:
ABCDS; AU022549; Ednra; Ednrb; endothelin B receptor; endothelin receptor non-selective type; endothelin receptor subtype B1; endothelin receptor type B; endothelin-B receptor; ETb; ET-B; Etb receptor; Et-b receptor; ETB1; ETBR; ET-BR; Et-b-r; Etb-svr; ETRB; ET-RB; ETR-b; HSCR; HSCR2; piebald; RP11-318G21.1; Sox10m1; WS4A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1910
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P24530
Gene Symbols:
EDNRB
Immunogen:
Synthetic peptide corresponding to a region within amino acids 9 and 101 of Endothelin B Receptor (Uniprot ID#P24530)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG