PIPA534713
HEF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA534713-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA534713 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
HEF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEDD9
Gene Alias
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18003, 4739
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.93 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O35177, Q14511
Gene Symbols
NEDD9
Immunogen
Recombinant fragment contains a sequence corresponding to a region within amino acids 115 and 444 of HEF1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: BCL-1
- Predicted reactivity: Mouse (85%), Rat (83%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation
- The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation
- These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases two active targets for drug development
- HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi
- HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells
- Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance
- This highlights the importance of studying the role of this family of proteins in cancer prognosis.
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Antigen: HEF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD9
Gene Alias: Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18003, 4739
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.93 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O35177, Q14511
Gene Symbols: NEDD9
Immunogen: Recombinant fragment contains a sequence corresponding to a region within amino acids 115 and 444 of HEF1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HEF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18003, 4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.93 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O35177, Q14511
Gene Symbols:
NEDD9
Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 115 and 444 of HEF1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CHRNA4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHRNA4
Gene Alias: a4 nicotinic receptor; acetylcholine receptor; acetylcholine receptor alpha 4 neural; acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit; Acra4; Acra-4; alpha4 nAChR; alpha4-nAChR; BFNC; cholinergic receptor; cholinergic receptor nicotinic alpha 4 subunit; cholinergic receptor, nicotinic alpha 4; cholinergic receptor, nicotinic, alpha 4 (neuronal); cholinergic receptor, nicotinic, alpha 4 subunit; cholinergic receptor, nicotinic, alpha polypeptide 4; CHRNA 4; Chrna4; EBN; EBN1; ENFL1; NACHR; nAChR alpha 4; NACHRA4; NACRA4; NARAC; neuronal acetylcholine receptor subunit alpha-4; Neuronal nicotinic acetylcholine receptor alpha 4 subunit; neuronal nicotinic acetylcholine receptor alpha-4 subunit
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1137
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.77 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P43681
Gene Symbols: CHRNA4
Immunogen: Recombinant fragment corresponding to a region within amino acids 53 and 280 of Nicotinic Acetylcholine Receptor alpha 4 (Uniprot ID#P43681)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CHRNA4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHRNA4
Gene Alias:
a4 nicotinic receptor; acetylcholine receptor; acetylcholine receptor alpha 4 neural; acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit; Acra4; Acra-4; alpha4 nAChR; alpha4-nAChR; BFNC; cholinergic receptor; cholinergic receptor nicotinic alpha 4 subunit; cholinergic receptor, nicotinic alpha 4; cholinergic receptor, nicotinic, alpha 4 (neuronal); cholinergic receptor, nicotinic, alpha 4 subunit; cholinergic receptor, nicotinic, alpha polypeptide 4; CHRNA 4; Chrna4; EBN; EBN1; ENFL1; NACHR; nAChR alpha 4; NACHRA4; NACRA4; NARAC; neuronal acetylcholine receptor subunit alpha-4; Neuronal nicotinic acetylcholine receptor alpha 4 subunit; neuronal nicotinic acetylcholine receptor alpha-4 subunit
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1137
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.77 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P43681
Gene Symbols:
CHRNA4
Immunogen:
Recombinant fragment corresponding to a region within amino acids 53 and 280 of Nicotinic Acetylcholine Receptor alpha 4 (Uniprot ID#P43681)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PIST
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GOPC
Gene Alias: 2210402P09Rik; AI844555; CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; Fused in glioblastoma; golgi associated PDZ and coiled-coil motif containing; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; Gopc; GOPC1; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57120
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9HD26
Gene Symbols: GOPC
Immunogen: Synthetic peptide corresponding to a region within amino acids 400 and 462 of PIST (Uniprot ID#Q9HD26)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PIST
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GOPC
Gene Alias:
2210402P09Rik; AI844555; CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; Fused in glioblastoma; golgi associated PDZ and coiled-coil motif containing; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; Gopc; GOPC1; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57120
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9HD26
Gene Symbols:
GOPC
Immunogen:
Synthetic peptide corresponding to a region within amino acids 400 and 462 of PIST (Uniprot ID#Q9HD26)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NTAL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LAT2
Gene Alias: AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7462
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.62 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9GZY6
Gene Symbols: LAT2
Immunogen: Synthetic peptide corresponding to a region within amino acids 181 and 243 of NTAL (Uniprot ID#Q9GZY6)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NTAL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LAT2
Gene Alias:
AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7462
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.62 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9GZY6
Gene Symbols:
LAT2
Immunogen:
Synthetic peptide corresponding to a region within amino acids 181 and 243 of NTAL (Uniprot ID#Q9GZY6)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG