PIPA534935
SETD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA534935-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA534935 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
SETD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Setd2
Gene Alias
4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29072
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9BYW2
Gene Symbols
Setd2
Immunogen
Recombinant protein fragment contains a sequence corresponding to a region within amino acids 511 and 2564 of HYPB/SETD2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, Jurkat
- Predicted reactivity: Rat (84%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate
- Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
- Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
- Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
- H3K36me3 also plays an essential role in the maintenance of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
- H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
- Required during angiogenesis
- Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.
Compare Similar Items
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Antigen: SETD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Setd2
Gene Alias: 4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29072
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9BYW2
Gene Symbols: Setd2
Immunogen: Recombinant protein fragment contains a sequence corresponding to a region within amino acids 511 and 2564 of HYPB/SETD2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SETD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Setd2
Gene Alias:
4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29072
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9BYW2
Gene Symbols:
Setd2
Immunogen:
Recombinant protein fragment contains a sequence corresponding to a region within amino acids 511 and 2564 of HYPB/SETD2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RSPO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RSPO1
Gene Alias: CRISTIN3; cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; RGD1565558; Roof plate-specific spondin-1; RP11-566C13.1; RSPO; RSPO1; Rspondin; R-spondin; R-spondin 1; R-spondin homolog; R-spondin homolog (Xenopus laevis); R-spondin-1; thrombospondin type 1 domain containing gene Rspondin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 284654
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q2MKA7
Gene Symbols: RSPO1
Immunogen: Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 292 of RSPO1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RSPO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RSPO1
Gene Alias:
CRISTIN3; cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; RGD1565558; Roof plate-specific spondin-1; RP11-566C13.1; RSPO; RSPO1; Rspondin; R-spondin; R-spondin 1; R-spondin homolog; R-spondin homolog (Xenopus laevis); R-spondin-1; thrombospondin type 1 domain containing gene Rspondin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
284654
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q2MKA7
Gene Symbols:
RSPO1
Immunogen:
Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 292 of RSPO1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PAK6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pak6
Gene Alias: 4732456M09; p21 (CDKN1A)-activated kinase 6; p21 (RAC1) activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated kinase 6; PAK5; PAK-5; PAK6; PAK-6; Serine/threonine-protein kinase PAK 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56924
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NQU5
Gene Symbols: Pak6
Immunogen: Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 681 of PAK6
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PAK6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pak6
Gene Alias:
4732456M09; p21 (CDKN1A)-activated kinase 6; p21 (RAC1) activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated kinase 6; PAK5; PAK-5; PAK6; PAK-6; Serine/threonine-protein kinase PAK 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56924
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NQU5
Gene Symbols:
Pak6
Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 681 of PAK6
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: hnRNP A2B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HNRNPA2B1
Gene Alias: 9130414A06Rik; DKFZp779B0244; EMBL:BAF79676.1}; FLJ22720; heterogeneous nuclear ribonucleoprotein A2; heterogeneous nuclear ribonucleoprotein A2/B1; heterogeneous nuclear ribonucleoprotein B0a; heterogeneous nuclear ribonucleoprotein B0b; heterogeneous nuclear ribonucleoprotein B1; heterogeneous nuclear ribonucleoproteins A2/B1; heterogeneous nuclear ribonucleoproteins A2/B1 {ECO:0000312; heterogenous nuclear ribonucleoprotein A2/B1; Hnrnp; hnRNP A2 / hnRNP B1; hnRNP A2/B1; hnrnp-A; HNRNPA2; HNRNPA2B1; hnrnpa2b1 {ECO:0000250; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; hypothetical protein; IBMPFD2; nuclear ribonucleoprotein particle A2 protein; OTTHUMP00000202465; OTTHUMP00000202466; RNPA2; SNRPB1; UniProtKB:P22626}
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3181, 362361, 53379
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.09 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: A7VJC2, O88569, P22626
Gene Symbols: HNRNPA2B1
Immunogen: Recombinant fragment contains a sequence corresponding to a region within amino acids 136 and 341 of hnRNP A2B1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
hnRNP A2B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HNRNPA2B1
Gene Alias:
9130414A06Rik; DKFZp779B0244; EMBL:BAF79676.1}; FLJ22720; heterogeneous nuclear ribonucleoprotein A2; heterogeneous nuclear ribonucleoprotein A2/B1; heterogeneous nuclear ribonucleoprotein B0a; heterogeneous nuclear ribonucleoprotein B0b; heterogeneous nuclear ribonucleoprotein B1; heterogeneous nuclear ribonucleoproteins A2/B1; heterogeneous nuclear ribonucleoproteins A2/B1 {ECO:0000312; heterogenous nuclear ribonucleoprotein A2/B1; Hnrnp; hnRNP A2 / hnRNP B1; hnRNP A2/B1; hnrnp-A; HNRNPA2; HNRNPA2B1; hnrnpa2b1 {ECO:0000250; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; hypothetical protein; IBMPFD2; nuclear ribonucleoprotein particle A2 protein; OTTHUMP00000202465; OTTHUMP00000202466; RNPA2; SNRPB1; UniProtKB:P22626}
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3181, 362361, 53379
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.09 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
A7VJC2, O88569, P22626
Gene Symbols:
HNRNPA2B1
Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 136 and 341 of hnRNP A2B1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG