PIPA534944
IL-22 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA534944-Each-of-1 | In Stock | ₹ 47,528.58 |
PIPA534944 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,528.58
GST (18%): ₹ 8,555.144
Total Price: ₹ 56,083.724
Antigen
IL-22
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL22
Gene Alias
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
50616, 50929
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9GZX6, Q9JJY9
Gene Symbols
IL22
Immunogen
Synthetic peptide contains a sequence corresponding to a region within amino acids 1 and 97 of IL22
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: mouse spleen
- Predicted reactivity: Mouse (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- IL-22 also known as IL-10-related T-cell derived inducible factor, is an alpha helical cytokine and is considered a member of the IFN-IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and the type I and II interferons
- IL-22 is produced mainly by activated T cells and NK cells
- In humans, the IL-22 gene is located on the q arm of chromosome 12, and is structurally related to IL10
- IL-22 acts by engaging the heterodimeric receptor complex consisting of primary receptor IL-22R1 and accessory receptor IL-10R2
- IL-22R1 also binds IL-20 and IL-24; IL-10R2 also binds IL-10, IL-27, IL-28, and IL-29
- Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway
- In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling
- IL-22 appears not to directly influence immune cells, and major targets of the cytokine appear to be nonimmune cells, such as cells of the skin, digestive and respiratory system, as well as hepatocytes, and keratinocytes
- IL-22 has been described as an effector cytokine of the Th17 lineage
- Along with IL-17A and IL-17F, IL-22 regulates genes associated with innate immunity of the skin
- IL-17A, IL-17F and IL-22 are all co-expressed by Th17 cells, however, they are differentially regulated
- The effects of IL-22 include induction of acute phase reactants and antimicrobial proteins, as well as increasing the mobility of keratinocytes
- IL-22 is highly expressed during chronic inflammation, and found to activate intracellular kinases and transcription factors
- IL-22 is critical for host defense against infections of extracellular pathogens, and promotes wound-healing responses
- IL-22 is upregulated in activated T cells
- IL-22 has been reported to mediate IL-23-induced acanthosis and dermal inflammation through activation of STAT3.
Compare Similar Items
Show Difference
Antigen: IL-22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL22
Gene Alias: Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50616, 50929
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9GZX6, Q9JJY9
Gene Symbols: IL22
Immunogen: Synthetic peptide contains a sequence corresponding to a region within amino acids 1 and 97 of IL22
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
IL-22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50616, 50929
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9GZX6, Q9JJY9
Gene Symbols:
IL22
Immunogen:
Synthetic peptide contains a sequence corresponding to a region within amino acids 1 and 97 of IL22
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TNFRSF11B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNFRSF11B
Gene Alias: LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18383, 4982
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.85 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O00300, O08712
Gene Symbols: TNFRSF11B
Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 67 of OPG
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TNFRSF11B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNFRSF11B
Gene Alias:
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18383, 4982
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.85 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O00300, O08712
Gene Symbols:
TNFRSF11B
Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 67 of OPG
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: DCTD
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DCTD
Gene Alias: 6030466N05Rik; dCMP deaminase; Dctd; Deoxycytidylate deaminase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1635
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P32321
Gene Symbols: DCTD
Immunogen: Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 178 of DCTD
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DCTD
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DCTD
Gene Alias:
6030466N05Rik; dCMP deaminase; Dctd; Deoxycytidylate deaminase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1635
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P32321
Gene Symbols:
DCTD
Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 178 of DCTD
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TDG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TDG
Gene Alias: C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114521, 6996
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13569
Gene Symbols: TDG
Immunogen: Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 410 of TDG
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TDG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TDG
Gene Alias:
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114521, 6996
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13569
Gene Symbols:
TDG
Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 410 of TDG
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG