PIPA535249

GFI1B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA535249-Each-of-1 In Stock ₹ 44,705.10

PIPA535249 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GFI1B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GFI1B

Gene Alias

BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14582, 8328

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O70237, Q5VTD9

Gene Symbols

GFI1B

Immunogen

KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human GFI1B

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • GFI1b (zinc finger protein GFI-1b) is an essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages
  • It is also a component of a RCOR-GFI-KDM1A-HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation
  • GFI1b also acts as a transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine signaling pathways
  • It also cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate
  • Mutations affecting the gene are associated with Bleeding disorder, platelet-type 17 (BDPLT17).

Compare Similar Items

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Thermo Scientific

PIPA535249

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Antigen:
GFI1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GFI1B

Gene Alias:
BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14582, 8328

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O70237, Q5VTD9

Gene Symbols:
GFI1B

Immunogen:
KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human GFI1B

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA535259

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Antigen:
PTGER4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTGER4

Gene Alias:
EP1; EP4; EP4R; MGC126583; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4; prostaglandin E receptor 4 (subtype EP4); prostaglandin E2 receptor EP4 subtype; prostaglandin E2 receptor type 4; prostanoid EP4 receptor; Ptger; PTGER2; Ptger4; Ptgerep4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19219, 5734

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P32240, P35408

Gene Symbols:
PTGER4

Immunogen:
KLH conjugated synthetic peptide between 242-269 amino acids from the central region of human PTGER4

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA535261

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Antigen:
RPLP0P6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPLP0P6

Gene Alias:
RPLP0P6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
220717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8NHW5

Gene Symbols:
RPLP0P6

Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RPLP0P6

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA535262

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Antigen:
SIRPB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRPB1

Gene Alias:
9930027N05Rik; CD172 antigen-like family member B; CD172b; CD172b antigen; DKFZp686A05192; signal regulatory protein beta 1; signal-regulatory protein beta 1; signal-regulatory protein beta 1A; signal-regulatory protein beta-1; Signal-regulatory protein beta-1 isoform 3; SIRP BETA 1; SIRP beta 1 cell surface protein; Sirpb; SIRPB1; Sirpb1a; SIRP-beta; SIRP-beta B; SIRP-BETA-1; SIRP-beta-1 isoform 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10326

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O00241

Gene Symbols:
SIRPB1

Immunogen:
KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human SIRPB1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG